 | 8-Cyclopentyl-1,3-dipropylxanthine | IC50 | 13.0 [1], 25.0 [2] |
| 8-Cyclopentyl-1,3-dipropylxanthine | Ki | 2.52 [1], 3.0 [2] |
 | 5'-N-Ethylcarboxamidoadenosine | IC50 | 0.21 [1] |
| 5'-N-Ethylcarboxamidoadenosine | Ki | 5.0 [1] |
 | 2-Cl-IB-Meca | Ki | 220.0 [1] |
 | IB-Meca | Ki | 51.0 [1] |
 | Caffeine | Ki | 44900.0 [1] |
 | Istradefylline | Ki | 2830.0 [1] |
 | N6-Cyclopentyladenosine | IC50 | 2.7 [1] |
 | 4-{2-[(7-Amino-2-Furan-2-Yl[1,2,4]triazolo[1,5-A][1,3,5]triazin-5-Yl)amino]ethyl}phenol | Ki | 255.0 [1] |
 | 2-Chloro-N6-cyclopentyladenosine | IC50 | 0.5 [1], 1.3 [2] |
 | 2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | Ki | 302.0 [1] |
 | Mcp-neca | Ki | 1197.0 [1], 1200.0 [2] |
 | 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine | Ki | 549.0 [1] |
 | 1-[11-Ethyl-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea | Ki | 1026.0 [1] |
 | CID 11248240 | Ki | 260.0 [1] |
 | N-(2-Furan-2-yl-6-pyrazol-1-yl-pyrimidin-4-yl)-acetamide | Ki | 9.2 [1], 10.2 [2] |
 | Preladenant | Ki | 295.0 [1], 996.0 [2], 1000.0 [3] |
 | 4-(Furan-2-yl)-10-[3-(4-methoxyphenyl)propyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine | Ki | 1.11 [1], 3.8 [2], 1111.0 [3] |
 | 2-Butyl-9-methyl-8-(triazol-2-yl)purin-6-amine | Ki | 71.8 [1], 79.2 [2], 100.0 [3] |
 | Tecadenoson | IC50 | 8.2 [1] |
| Tecadenoson | Ki | 2.05 [1], 3.0 [2], 65.0 [3] |
 | (2R,3R,4S,5R)-2-(6-Amino-2-(phenylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Ki | 391.0 [1] |
 | (2R,3R,4S)-2-(6-(3-Iodobenzylamino)-2-chloro-9H-purin-9-yl)-tetrahydrothiophene-3,4-diol | Ki | 2490.0 [1] |
 | (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(4-methoxyphenylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol | Ki | 71.0 [1], 195.0 [2], 842.0 [3], 1990.0 [4] |
 | 8-(4-(4-Benzylpiperazin-1-ylsulfonyl)phenyl)-1-propyl-1H-purine-2,6(3H,7H)-dione | Ki | 2067.0 [1], 2070.0 [2] |
 | (2S,3S,4R,5R)-5-[2-Chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N,N-dimethyloxolane-2-carboxamide | Ki | 5870.0 [1] |
 | (2S,3S,4R,5R)-5-[2-Chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide | Ki | 6220.0 [1] |
 | (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]-N-methylthiolane-2-carboxamide | Ki | 17.3 [1], 20.2 [2] |
 | 5-Methyl-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine | Ki | 70.0 [1] |
 | 2,5-Diphenylpyrazolo[4,3-d]pyrimidin-7-amine | Ki | 75.0 [1] |
 | 5-Benzyl-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine | Ki | 150.0 [1] |
 | 2-Chloroadenosine | Ki | 1.39 [1], 2.8 [2], 18.4 [3] |
 | (R)-N-(1-Methyl-2-phenylethyl)adenosine | IC50 | 830.0 [1] |
| (R)-N-(1-Methyl-2-phenylethyl)adenosine | Ki | 2.0 [1] |
 | Rolofylline | Ki | 0.29 [1], 0.72 [2] |
 | Fscpx | IC50 | 10.0 [1], 11.8 [2] |
 | Cvt-6883 | Ki | 1940.0 [1], 10000.0 [2] |
 | (+)-(R)-((E)-3-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)acryloyl)-2-piperidineethanol | Ki | 0.49 [1], 18.0 [2] |
 | Tonapofylline | Ki | 7.0 [1], 7.4 [2] |
 | Binodenoson | Ki | 169.0 [1], 48000.0 [2] |
 | 7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine | Ki | 0.16 [1], 300.0 [2], 670.0 [3] |
 | CID 10046145 | Ki | 2500.0 [1] |
 | 4-(Furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine | Ki | 1.0 [1] |
 | 1-[4-(Furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea | Ki | 1097.0 [1] |
 | Unii-djf621DE4F | Ki | 369.0 [1], 1000.0 [2] |
 | 1-(3-Chlorophenyl)-3-[11-ethyl-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea | Ki | 249.0 [1] |
 | 1-[11-Butyl-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea | Ki | 296.0 [1] |
 | 1-(3-Chlorophenyl)-3-[4-(furan-2-yl)-11-propyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea | Ki | 30.0 [1] |
 | Trabodenoson | Ki | 0.97 [1] |
 | 5-Butyl-8-[4-(trifluoromethyl)phenyl]-1H-[1,2,4]triazolo[5,1-f]purine | IC50 | 10000.0 [1] |
| 5-Butyl-8-[4-(trifluoromethyl)phenyl]-1H-[1,2,4]triazolo[5,1-f]purine | Ki | 4.0 [1], 10000.0 [2] |
 | N-[2-[[2-Phenyl-6-[4-(3-phenylpropyl)piperazine-1-carbonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]ethyl]acetamide | Ki | 37.0 [1], 450.0 [2] |
 | N-[4-(Furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-naphthalen-1-ylacetamide | Ki | 710.0 [1], 1100.0 [2] |
 | (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(methylamino)-2-(2-phenylethynyl)purin-9-yl]oxolane-3,4-diol | Ki | 1690.0 [1] |
 | 4-Benzyl-7-methyl-2-propyl-6H-purino[7,8-a]imidazole-1,3-dione | Ki | 1000.0 [1] |
 | 2-(4-Methyl-1H-1,3-benzodiazol-2-yl)quinoxaline | Ki | 8000.0 [1] |
 | 2-Amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[1,2-d]pyrimidin-5-one | Ki | 48.2 [1] |
 | (1S,2R,3S,4R,5S)-4-[2-Chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide | Ki | 136.0 [1] |
 | 7-Bromo-2-phenyl-[1,8]naphthyridin-4-ol | Ki | 0.79 [1], 336.0 [2], 360.0 [3] |
 | (5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-((R)-1-phenyl-ethyl)-amine | IC50 | 1607.0 [1], 1981.0 [2] |
| (5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-((R)-1-phenyl-ethyl)-amine | Ki | 981.0 [1] |
 | N-Cyclohexyl-7-methyl-2-phenyl-1,8-naphthyridin-4-amine | Ki | 31.62 [1], 448.0 [2], 560.0 [3] |
 | N-(2,6-Diphenylpyrimidin-4-yl)acetamide | Ki | 31.2 [1], 37.5 [2] |
 | 4-Benzyl-7-ethyl-2-propyl-8H-purino[7,8-a]pyrrole-1,3-dione | Ki | 1000.0 [1] |
 | (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(methylamino)-2-(4-pyridin-2-ylpyrazol-1-yl)purin-9-yl]oxolane-3,4-diol | Ki | 3800.0 [1] |
 | 2-(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)-N-(4-iodophenyl)acetamide | Ki | 293.0 [1], 295.12 [2] |
 | N-(2-Furan-2-yl-6-pyrazol-1-yl-pyrimidin-4-yl)-2-(4-methyl-piperazin-1-yl)-acetamide | Ki | 266.0 [1], 270.0 [2] |
 | 2-(3,4-Dimethoxyphenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]acetamide | Ki | 1000.0 [1] |
 | N-[6-(3,5-Dimethylpyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-(4-methylpiperazin-1-yl)acetamide | Ki | 850.0 [1] |
 | 2-(6-Amino-8-bromo-9H-purin-9-yl)ethanol | Ki | 1500.0 [1] |
 | (1R,2R,3S,4R,5S)-4-[2-Chloro-6-[(3-chlorophenyl)methylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol | Ki | 1600.0 [1], 3070.0 [2] |
 | 4-[6-Amino-9-methyl-8-(triazol-2-yl)purin-2-yl]butan-2-one | Ki | 192.0 [1], 197.0 [2], 200.0 [3] |
 | 4-[6-Amino-9-methyl-8-(triazol-2-yl)purin-2-yl]butan-2-ol | Ki | 24.0 [1], 27.0 [2], 34.0 [3] |
 | (1R,2R,3S,4R,5S)-4-[2-Chloro-6-(dicyclopropylmethylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol | Ki | 47.9 [1], 48.0 [2] |
 | (2S,3S,4R,5R)-5-[2-Chloro-6-(methylamino)purin-9-yl]-3,4-dihydroxy-N-methylthiolane-2-carboxamide | Ki | 1330.0 [1] |
 | Unii-29S2U9drgs | Ki | 200.0 [1], 10000.0 [2] |
 | 7-Dimethylamino-2-phenyl-[1,8]naphthyridin-4-ol | Ki | 0.63 [1], 980.0 [2], 1370.0 [3] |
 | 8-Bromo-9-propyl-9H-purin-6-ylamine | Ki | 1100.0 [1] |
 | 2-Phenyl-5-(3-phenylpropyl)pyrazolo[4,3-d]pyrimidin-7-amine | IC50 | 43.0 [1] |
| 2-Phenyl-5-(3-phenylpropyl)pyrazolo[4,3-d]pyrimidin-7-amine | Ki | 5.3 [1], 5.31 [2] |
 | 7-Methyl-2-propyl-[1,8]naphthyridin-4-ol | Ki | 50.12 [1], 1447.0 [2], 1500.0 [3] |
 | 7-Amino-2-methyl-1,8-naphthyridin-4-ol | Ki | 10000.0 [1] |
 | 2-(3-Amino-6-imino-4,5-disulfoxanthen-9-yl)-5-[6-[4-[4-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-4-oxobutyl]triazol-1-yl]hexylcarbamoyl]benzoic acid | Ki | 87.0 [1], 87.1 [2] |
 | (2S,3R,4S,5S,6R)-2-[4-[[(3S,4R,5S)-4-[[(2R,3S,4S,5S)-3,4-Dihydroxy-5-(hydroxymethyl)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methoxymethyl]-3-hydroxy-5-(4-hydroxy-3-methoxyphenyl)oxolan-3-yl]methyl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | Ki | 26.0 [1], 23600.0 [2], 31000.0 [3] |
 | (2S)-2-[(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-4-methylpentan-1-ol | IC50 | 1754.0 [1], 1910.0 [2] |
| (2S)-2-[(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-4-methylpentan-1-ol | Ki | 951.0 [1] |
 | (5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyridin-4-ylmethyl-amine | IC50 | 222.0 [1], 262.0 [2] |
| (5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyridin-4-ylmethyl-amine | Ki | 132.0 [1] |
 | 1-[2-[(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl]imidazolidin-2-one | IC50 | 364.0 [1], 422.0 [2] |
| 1-[2-[(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl]imidazolidin-2-one | Ki | 144.0 [1] |
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