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ADAM9 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
IlomastatIC501.0 [1], 56.3 [2]
ApratastatIC5085.0 [1]
Grassystatin AIC5010000.0 [1], 46100.0 [2]
(6S,7S)-N-Hydroxy-5-methyl-6-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbonyl]-5-azaspiro[2.5]octane-7-carboxamideIC505000.0 [1]
(6S,7S)-N-Hydroxy-5-methyl-6-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbonyl]-5-azaspiro[2.5]octane-7-carboxamideKi2200.0 [1]
PepstatinIC5056.3 [1]
Unii-Q56UE7E40YIC505000.0 [1]
(3S)-2-[Ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC5010000.0 [1]
Grassystatin BIC5085500.0 [1]
N-Hydroxy-2-[methoxy-(4-methoxyphenyl)phosphoryl]-3,4-dihydro-1H-isoquinoline-3-carboxamideIC5070.0 [1]
2-[Ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50230.0 [1]
2-[Ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC5010000.0 [1]
(3S)-2-[Ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC5010000.0 [1]
5-((5-Methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-methylimidazolidine-2,4-dioneKi10000.0 [1]
6-[Ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-7,8-dihydro-5H-pyrido[3,4-b]pyrazine-7-carboxamideIC50560.0 [1]
N-Hydroxy-3-[methyl-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]-1-(2-methylpropanoyl)azetidine-3-carboxamideIC5090.0 [1]
N-Hydroxy-1-(3-methylbutanoyl)-3-[methyl-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]azetidine-3-carboxamideIC50480.0 [1]
1-(2,2-Dimethylpropanoyl)-N-hydroxy-4-[4-[(2-methyl-5,6,7,8-tetrahydroquinolin-4-yl)methoxy]phenyl]sulfonylpiperazine-2-carboxamideIC5010000.0 [1]
Grassystatin CIC50100000.0 [1]
2-[2-(Diethylamino)ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC501140.0 [1]
2-[Ethoxy-(4-phenoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50260.0 [1]
2-[[4-(4-Aminophenoxy)phenyl]-ethoxyphosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC501670.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)-(2-phenylethoxy)phosphoryl]-3,4-dihydro-1H-isoquinoline-3-carboxamideIC503110.0 [1]
2-[Ethoxy-(4-pyridin-4-yloxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50660.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)-[2-(4-phenylphenyl)ethoxy]phosphoryl]-3,4-dihydro-1H-isoquinoline-3-carboxamideIC503560.0 [1]
2-[Cyclohexylmethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC501340.0 [1]
2-[Ethoxy(thiophen-2-yl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50890.0 [1]
2-[(4-Aminophenyl)-ethoxyphosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50660.0 [1]
2-[Ethoxy(pyridin-4-yl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC502600.0 [1]
2-[Ethoxy-(2-fluorophenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC501060.0 [1]
7-Amino-2-[ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50190.0 [1]
2-[Ethoxy-(3-fluorophenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50830.0 [1]
2-[Ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxamideIC50800.0 [1]
(2-Hydroxycarbamoyl-pyrrolidin-1-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl esterIC5010000.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)-(2-pyridin-2-ylethoxy)phosphoryl]-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50180.0 [1]
2-[Ethoxy-(4-fluorophenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50300.0 [1]
2-[Ethoxy-(4-methylphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC501890.0 [1]
(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-styryl-phosphinic acid ethyl esterIC50910.0 [1]
(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenyl-phosphinic acid ethyl esterIC50370.0 [1]
2-[2-Ethoxyethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50510.0 [1]
Benzyl 4-[ethoxy-(4-methoxyphenyl)phosphoryl]-3-(hydroxycarbamoyl)piperazine-1-carboxylateIC50430.0 [1]
5-[Ethoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-6,7-dihydro-4H-thieno[3,2-c]pyridine-6-carboxamideIC50520.0 [1]
2-[Ethoxy-(4-phenylphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC501960.0 [1]
2-[Ethoxy-[4-(2-ethoxyethoxy)phenyl]phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC5070.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)-propan-2-yloxyphosphoryl]-3,4-dihydro-1H-isoquinoline-3-carboxamideIC502240.0 [1]
2-[Hexoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC501600.0 [1]
2-[Ethoxy(2-phenylethyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50700.0 [1]
2-[Butoxy-(4-methoxyphenyl)phosphoryl]-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamideIC50810.0 [1]
(2S)-N-Hydroxy-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]-2-(4-propan-2-ylsulfonylpiperazin-1-yl)propanamideIC5010000.0 [1]
(2S)-2-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-N-hydroxy-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]propanamideIC509254.0 [1]
(2S)-2-(4-Ethylpiperazin-1-yl)-N-hydroxy-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]propanamideIC503054.0 [1]
(2S)-N-Hydroxy-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]-2-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]propanamideIC5010000.0 [1]
(2S)-N-Hydroxy-2-[4-[(4-methylphenyl)methyl]piperazin-1-yl]-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]propanamideIC5010000.0 [1]
(2S)-N-Hydroxy-2-[4-(2-methylpropanoyl)piperazin-1-yl]-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]propanamideIC5010000.0 [1]
(2S)-N-Hydroxy-2-[4-(2-methylpropylsulfonyl)piperazin-1-yl]-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]propanamideIC5010000.0 [1]
(2S)-N-Hydroxy-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]-2-(4-methylsulfonylpiperazin-1-yl)propanamideIC5010000.0 [1]
4-But-2-ynoxy-N-[(2S)-3-(hydroxyamino)-2-(4-methylsulfonylpiperazin-1-yl)-3-oxopropyl]benzamideIC503251.0 [1]
N-[(2S)-3-(Hydroxyamino)-2-(4-methylsulfonylpiperazin-1-yl)-3-oxopropyl]-4-[(2-methylquinolin-4-yl)methoxy]benzamideIC5010000.0 [1]
N-[(2S)-3-(Hydroxyamino)-3-oxo-2-piperidin-1-ylpropyl]-4-[(2-methylquinolin-4-yl)methoxy]benzamideIC5010000.0 [1]
N-[(2S)-3-(Hydroxyamino)-3-oxo-2-piperidin-1-ylpropyl]-4-[(2-phenylpyridin-4-yl)methoxy]benzamideIC5010000.0 [1]
N-[(2S)-3-(Hydroxyamino)-3-oxo-2-piperidin-1-ylpropyl]-4-(pyridin-4-ylmethoxy)benzamideIC5010000.0 [1]
N-[(2S)-2-(Diethylamino)-3-(hydroxyamino)-3-oxopropyl]-4-[(2-methylquinolin-4-yl)methoxy]benzamideIC5010000.0 [1]
N-[2-(4-Benzylpiperazin-1-yl)-3-(hydroxyamino)-3-oxopropyl]-4-[[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]methoxy]benzamideIC5010000.0 [1]
N-Hydroxy-4-[4-(4-hydroxybut-2-ynoxy)phenyl]sulfonyl-2,2-dimethylthiomorpholine-3-carboxamideIC5085.0 [1]
Items per page: 1 - 10 of 64
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References

This online tool may be cited as follows

MLA

"Quest Database™ ADAM9 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/adam9-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ ADAM9 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/adam9-inhibitors-ic50-ki.
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