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Activin receptor type-1B Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinolineIC5043.29 [1], 1825.0 [2]
StaurosporineIC509118.0 [1]
DorsomorphinIC5025740.0 [1]
DoramapimodIC5044000.0 [1]
GalunisertibIC50199.0 [1]
2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridineIC5070.0 [1]
4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamideIC501000.0 [1]
Benzamide, 3-((4-(6-methyl-2-pyridinyl)-5-(6-quinoxalinyl)-1H-imidazol-2-yl)methyl)-IC5023.0 [1]
VactosertibIC5013.0 [1]
5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinolineIC504090.0 [1]
4-[6-(4-Propan-2-yloxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinolineIC509622.0 [1]
Khk-IN-1IC5040000.0 [1]
Dimethyl-{2-[(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-2-pyridinyl}phenyl)oxy]ethyl}amineIC5046.0 [1]
4-(6-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinolineIC501840.0 [1]
5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamideIC5010000.0 [1]
1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)ureaIC5035000.0 [1]
CID 60182364IC50183.0 [1]
CID 60182389IC50326.0 [1]
4-(4-(3-(1H-Pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)morpholineIC505930.0 [1]
2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-oneIC5010000.0 [1]
N-[4-[3-[5-(Trideuteriomethoxy)pyridin-2-yl]-1H-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2-yl]acetamideIC50100.0 [1]
N-[4-[3-[6-(Difluoromethyl)pyridin-2-yl]-1H-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2-yl]acetamideIC50100.0 [1]
(4S,9S,10S)-9,10,18-Trihydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),15,17-triene-2,8-dioneIC502761.0 [1]
Alk2-IN-2IC5018330.0 [1]
2-Pyrazol-1-yl-4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridineIC50882.0 [1]
2-(1-Methylpyrazol-4-yl)-4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridineIC50224.0 [1]
1-Methyl-4-[5-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]pyridin-2-yl]piperazineIC50108.0 [1]
N,N-Dimethyl-3-[5-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]pyridin-2-yl]oxypropan-1-amineIC5018.0 [1]
2-Imidazol-1-yl-4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridineIC50956.0 [1]
6-(4-Piperazin-1-ylphenyl)-3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidineIC503420.0 [1]
8-N-(Cyclopropylmethyl)-4-N-(2-methylsulfanylphenyl)-2-(4-piperidin-4-ylpiperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamineIC5010000.0 [1]
3-Methyl-6-[2-(6-methylpyridin-2-yl)pyrazol-3-yl]quinazolin-4-oneIC5059.0 [1]
N-[4-[(6-Chloro-[1,3]dioxolo[4,5-B]pyridin-7-Yl)amino]-2-Pyridyl]cyclopropanecarboxamideIC5031.0 [1]
Items per page: 1 - 10 of 33
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References

This online tool may be cited as follows

MLA

"Quest Database™ Activin receptor type-1B Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/activin-receptor-type-1b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Activin receptor type-1B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/activin-receptor-type-1b-inhibitors-ic50-ki.
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