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Acid ceramidase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
CarmofurIC5020.7 [1], 190.8 [2], 758.5 [3]
N-[(4-Methylphenyl)methyl]benzimidazole-1-carboxamideIC5014.8 [1], 505.3 [2], 928.3 [3]
N-Benzylbenzimidazole-1-carboxamideIC5022.5 [1], 1061.5 [2], 2799.0 [3]
2-Methoxy-N-(4-phenylbutyl)benzimidazole-1-carboxamideIC5013.9 [1], 966.9 [2], 2784.1 [3]
N-(4-Phenylbutyl)benzimidazole-1-carboxamideIC502.5 [1], 75.6 [2], 229.7 [3]
D-NmappdIC5010000.0 [1]
CID 60150550IC5077000.0 [1]
N-[(E,2R)-1-Hydroxy-4-tridecylsulfanylbut-3-en-2-yl]-2,2-dimethylpropanamideIC5051000.0 [1]
4-Tert-butyl-N-[(E,2R)-1-hydroxy-4-tridecylsulfanylbut-3-en-2-yl]benzamideIC50315000.0 [1]
n-OleoylethanolamineKi500000.0 [1]
D-Erythro-MAPPIC501000.0 [1]
CID 78319072IC506270.0 [1]
N-Hexylbenzimidazole-1-carboxamideIC506.6 [1]
2-Oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5064.0 [1]
6-(4-Fluorophenyl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5079.0 [1]
5-Chloro-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5015.0 [1]
7-Methyl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5023.0 [1]
N-[4-(4-Nitrophenyl)butyl]-2-oxo-1,3-benzoxazole-3-carboxamideIC50312.0 [1]
2-Oxo-6-phenyl-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5084.0 [1]
5-Nitro-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC503.0 [1]
2-Oxo-N-(4-thiophen-2-ylbutyl)-1,3-benzoxazole-3-carboxamideIC5037.0 [1]
2-Oxo-N-[(4-propylphenyl)methyl]-1,3-benzoxazole-3-carboxamideIC5019.0 [1]
N-(4-Naphthalen-2-ylbutyl)-2-oxo-1,3-benzoxazole-3-carboxamideIC5071.0 [1]
6-Fluoro-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5031.0 [1]
6-(4-Methoxyphenyl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5067.0 [1]
2-Oxo-N-(6-phenylhexyl)-1,3-benzoxazole-3-carboxamideIC5051.0 [1]
2-Oxo-N-(5-phenylpentyl)-1,3-benzoxazole-3-carboxamideIC5054.0 [1]
2-Oxo-N-(3-phenylpropyl)-1,3-benzoxazole-3-carboxamideIC5055.0 [1]
2-Oxo-4-phenyl-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC500.8 [1]
6-Chloro-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5033.0 [1]
6-(4-Chlorobenzoyl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5014.0 [1]
N-[4-(4-Methylphenyl)butyl]-2-oxo-1,3-benzoxazole-3-carboxamideIC5025.0 [1]
5-Methyl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC50117.0 [1]
7-Bromo-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5018.0 [1]
5-(4-Methoxyphenyl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5067.0 [1]
6-Methyl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5066.0 [1]
5-(4-Fluorophenyl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5056.0 [1]
5-Bromo-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5022.0 [1]
5,6-Dichloro-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5018.0 [1]
5-Fluoro-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5012.0 [1]
2-Oxo-7-phenyl-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5091.0 [1]
6-Benzoyl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5029.0 [1]
6-Nitro-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC503.0 [1]
N-[4-(4-Methoxyphenyl)butyl]-2-oxo-1,3-benzoxazole-3-carboxamideIC5063.0 [1]
2-Oxo-5-phenyl-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5042.0 [1]
N-[4-(4-Fluorophenyl)butyl]-2-oxo-1,3-benzoxazole-3-carboxamideIC5075.0 [1]
(2,2-Difluoro-1,3-benzodioxol-5-yl)methyl N-[(3S)-2-oxoazetidin-3-yl]carbamateIC508090.0 [1]
5-Benzoyl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5024.0 [1]
2-Oxo-N-(4-phenylbutyl)-5-(trifluoromethyl)-1,3-benzoxazole-3-carboxamideIC5018.0 [1]
2-Oxo-N-(4-phenylbutyl)-6-(trifluoromethyl)-1,3-benzoxazole-3-carboxamideIC5020.0 [1]
2-Oxo-N-(2-phenylmethoxyethyl)-1,3-benzoxazole-3-carboxamideIC50649.0 [1]
N-(2-Benzylsulfanylethyl)-2-oxo-1,3-benzoxazole-3-carboxamideIC5065.0 [1]
2-Oxo-N-(4-phenylbutyl)-3H-benzimidazole-1-carboxamideIC5010000.0 [1]
2-Amino-N-hexylbenzimidazole-1-carboxamideIC502.4 [1]
1-(1H-Benzimidazol-2-yl)-3-(4-phenylbutyl)ureaIC5010000.0 [1]
N-Hexyltriazolo[4,5-b]pyridine-1-carboxamideIC502.2 [1]
N-Hexyl-1,3-dioxoisoindole-2-carboxamideIC507.0 [1]
2-Amino-N-[(2-methylphenyl)methyl]benzimidazole-1-carboxamideIC5068.4 [1]
1-(1,3-Benzoxazol-2-yl)-3-hexylureaIC5010000.0 [1]
N-(4-Phenylbutyl)triazolo[4,5-b]pyridine-1-carboxamideIC501.3 [1]
1,3-Dioxo-N-(4-phenylbutyl)isoindole-2-carboxamideIC502.4 [1]
N-[(3-Methylphenyl)methyl]benzimidazole-1-carboxamideIC508.3 [1]
N-(4-Phenylbutyl)indazole-1-carboxamideIC504.7 [1]
1-(1,3-Benzoxazol-2-yl)-3-(4-phenylbutyl)ureaIC5010000.0 [1]
N-[(2-Methylphenyl)methyl]benzimidazole-1-carboxamideIC5055.9 [1]
2-Amino-N-(4-phenylbutyl)benzimidazole-1-carboxamideIC500.9 [1]
N-Hexylindazole-1-carboxamideIC509.9 [1]
1-(1H-Benzimidazol-2-yl)-3-hexylureaIC5010000.0 [1]
2-Amino-N-[(4-methylphenyl)methyl]benzimidazole-1-carboxamideIC507.0 [1]
2-Methyl-N-(4-phenylbutyl)benzimidazole-1-carboxamideIC501.0 [1]
1-(1,3-Benzothiazol-2-yl)-3-(4-phenylbutyl)ureaIC5010000.0 [1]
4-Cyclohexylbutyl N-[(2S,3S)-2-methyl-1-(4-methylsulfonylphenoxy)-4-oxoazetidin-3-yl]carbamateIC502020.0 [1]
2-Oxo-1-N,3-N-bis(4-phenylbutyl)benzimidazole-1,3-dicarboxamideIC5021.0 [1]
2-Amino-N-[(3-methylphenyl)methyl]benzimidazole-1-carboxamideIC508.5 [1]
4-Cyclohexylbutyl N-[(2S,3S)-2-methyl-4-oxo-1-phenoxyazetidin-3-yl]carbamateIC50300.0 [1]
2-Oxo-N-(2-phenylethyl)-1,3-benzoxazole-3-carboxamideIC50121.0 [1]
1-(1,3-Benzothiazol-2-yl)-3-hexylureaIC5010000.0 [1]
N-Hexylbenzotriazole-1-carboxamideIC504.1 [1]
N-Hexyl-2,4-dioxo-5-phenylpyrimidine-1-carboxamideIC50155.0 [1]
5-Bromo-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamideIC5035.0 [1]
4-(4,4-Difluorocyclohexyl)butyl N-[(3S)-2-oxoazetidin-3-yl]carbamateIC5010490.0 [1]
(4-Butylphenyl)methyl N-[(3S)-2-oxoazetidin-3-yl]carbamateIC50390.0 [1]
(4-Cyclohexylphenyl)methyl N-[(3S)-2-oxoazetidin-3-yl]carbamateIC501510.0 [1]
N-(4-Phenylbutyl)benzotriazole-1-carboxamideIC502.1 [1]
CID 90425119IC502410.0 [1]
6-Bromo-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamideIC5031.0 [1]
2-Amino-N-benzylbenzimidazole-1-carboxamideIC5029.3 [1]
Methyl 5-bromo-3-(hexylcarbamoyl)-2,6-dioxopyrimidine-1-carboxylateIC50270.0 [1]
2-Methylpropyl 5-bromo-3-(hexylcarbamoyl)-2,6-dioxopyrimidine-1-carboxylateIC5014.0 [1]
Items per page: 1 - 10 of 89
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References

This online tool may be cited as follows

MLA

"Quest Database™ Acid ceramidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/acid-ceramidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Acid ceramidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/acid-ceramidase-inhibitors-ic50-ki.
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