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6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
2-Amino-N-[4-(2-amino-3-cyano-1-ethylindol-5-yl)oxyphenyl]acetamideIC509180.0 [1]
2-Amino-N-[4-(2-amino-3-cyano-1-methylindol-5-yl)oxyphenyl]acetamideIC5021100.0 [1]
(2R)-2-Amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]-3-hydroxypropanamideIC50100000.0 [1]
2-Amino-N-[4-[2-amino-3-cyano-1-[2-(dimethylamino)-2-oxoethyl]indol-5-yl]oxyphenyl]acetamideIC506840.0 [1]
2-Amino-N-[4-(3-cyano-1-ethylindol-5-yl)oxyphenyl]acetamideIC5022800.0 [1]
(2s)-2-Amino-N-[4-[(2-Amino-3-Cyano-1h-Indol-5-Yl)oxy]phenyl]-3-Hydroxy-PropanamideIC5026900.0 [1]
(2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)indol-5-yl]amino]phenyl]pyrrolidine-2-carboxamideIC506150.0 [1]
(2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)indol-5-yl]-methylamino]phenyl]pyrrolidine-2-carboxamideIC50141.0 [1]
(2S)-N-[4-[3-Cyano-1-(2-methylpropyl)indol-5-yl]sulfanylphenyl]pyrrolidine-2-carboxamideIC50190.0 [1]
(2S)-N-[4-[3-Cyano-1-(2-methylpropyl)indol-5-yl]sulfonylphenyl]pyrrolidine-2-carboxamideIC50100000.0 [1]
(2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)indol-5-yl]methyl]phenyl]pyrrolidine-2-carboxamideIC501450.0 [1]
AZ Pfkfb3 26IC50384.0 [1]
2-Amino-N-[4-[2-amino-3-cyano-1-(2-methylpropyl)indol-5-yl]oxyphenyl]acetamideIC502520.0 [1]
N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-2-(methylamino)acetamideIC5024890.0 [1]
N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-2-(dimethylamino)acetamideIC5076100.0 [1]
(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamideIC501820.0 [1]
(2R)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamideIC50100000.0 [1]
(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-N-methylpyrrolidine-2-carboxamideIC5076500.0 [1]
(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]piperidine-2-carboxamideIC5022000.0 [1]
(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-N-methyl-5-oxopyrrolidine-2-carboxamideIC5023700.0 [1]
(2S)-N-[4-[3-Cyano-1-[2-(methylamino)-2-oxoethyl]indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamideIC502350.0 [1]
(2S)-N-[4-[3-Cyano-1-[2-(dimethylamino)ethyl]indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamideIC50100000.0 [1]
(2S)-N-[4-[3-Cyano-1-(oxan-4-ylmethyl)indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamideIC50429.0 [1]
(2S)-N-[4-(3-Cyano-1-phenylindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamideIC50374.0 [1]
(2S)-N-[4-[3-Cyano-1-(2-methyl-1-oxo-3H-isoindol-5-yl)indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamideIC50108.0 [1]
(2S)-N-[4-(1-Benzyl-3-cyanoindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamideIC50188.0 [1]
(2S)-N-[4-[3-Cyano-1-(2-methylpropyl)indazol-5-yl]oxyphenyl]pyrrolidine-2-carboxamideIC5015.0 [1]
(2S)-N-[4-[3-Cyano-1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]indazol-5-yl]oxyphenyl]pyrrolidine-2-carboxamideIC5025.0 [1]
2-Amino-N-[4-[[3-(1-methylpyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]acetamideIC5011800.0 [1]
(2S)-N-[4-[[3-(1-Methylpyrazol-4-yl)-1H-indol-5-yl]oxy]phenyl]pyrrolidine-2-carboxamideIC503570.0 [1]
2-Amino-N-[4-(2-Amino-1-Benzyl-3-Cyano-Indol-5-Yl)oxyphenyl]acetamideIC501480.0 [1]
CID 91668554IC50159.0 [1]
2-Azanyl-N-[4-[(3-Cyano-1h-Indol-5-Yl)oxy]phenyl]ethanamideIC5063200.0 [1]
(2s)-N-[4-[1-Methyl-3-(1-Methylpyrazol-4-Yl)indol-5-Yl]oxyphenyl]pyrrolidine-2-CarboxamideIC50818.0 [1]
5-(4-Acetylaminophenoxy)-2-amino-1H-indole-3-carbonitrileIC50100000.0 [1]
2-Amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]acetamideIC5053800.0 [1]
Items per page: 1 - 10 of 36
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References

This online tool may be cited as follows

MLA

"Quest Database™ 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/6-phosphofructo-2-kinase-fructose-2-6-bisphosphatase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/6-phosphofructo-2-kinase-fructose-2-6-bisphosphatase-2-inhibitors-ic50-ki.
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