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5'-nucleotidase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Phosphomethylphosphonic acid adenosyl esterIC503800.0 [1], 21400.0 [2], 23600.0 [3]
[[(2R,3R,4S,5R)-5-(6-Amino-2-chloropurin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acidIC50180.0 [1], 240.0 [2], 3200.0 [3]
[[(2R,3S,4S,5R)-5-(6-Amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acidIC502200.0 [1], 111900.0 [2]
[[(2R,3S,5R)-5-(6-Amino-2-chloropurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acidIC502000.0 [1], 147100.0 [2]
Sulfamic acidIC5042100.0 [1]
Sulfanilic acidIC508200.0 [1]
4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acidIC5021800.0 [1]
2-(4-Aminophenyl)-6-methyl-1,3-benzothiazole-7-sulfonic acidIC5013500.0 [1]
6-Amino-4-hydroxy-2-naphthalenesulfonic acidIC501320.0 [1]
2-[[(Z)-(6-Chloro-2-methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi64.0 [1]
4-[[(Z)-(6,8-Dichloro-2-methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi138.0 [1]
3-[[(Z)-(6,8-Dichloro-2-methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi46.0 [1]
2-[[(Z)-(6,8-Dichloro-2-methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi42.0 [1]
3-[[(Z)-(2-Butoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi18.0 [1]
4-[[(Z)-(2-Methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi338.0 [1]
3-[[(Z)-(2-Methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi18.0 [1]
2-[[(Z)-(2-Methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi91.0 [1]
4-[[(Z)-(2-Butoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi63.0 [1]
4-[[(Z)-(6-Chloro-2-methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi79.0 [1]
3-[[(Z)-(6-Chloro-2-methoxy-4-oxochromen-3-ylidene)methyl]amino]benzenesulfonamideKi27.0 [1]
4-[[(Z)-(4-Oxo-2-propan-2-yloxychromen-3-ylidene)methyl]amino]benzenesulfonamideKi53.0 [1]
3-[[(Z)-(4-Oxo-2-propan-2-yloxychromen-3-ylidene)methyl]amino]benzenesulfonamideKi14.0 [1]
Chembl4129881IC503162.28 [1]
Chembl4127683IC5015.85 [1]
4-Amino-3-hydroxy-7-nitronaphthalene-1-sulfonic acidIC5041000.0 [1]
8-Bromo-7-chloro-3-[(7-fluoro-1H-indol-5-yl)amino]-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-5-olIC5063.1 [1]
7-Chloro-3-(1H-indol-4-ylamino)-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-5-olIC506.5 [1]
7-Chloro-3-(4-methylanilino)-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-5-olIC501000.0 [1]
7-Fluoro-3-(3-hydroxyanilino)-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-5-olIC50100.0 [1]
6-(Carbamoylamino)-4-hydroxynaphthalene-2-sulfonic acidIC5030500.0 [1]
4-(3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acidIC506100.0 [1]
2-(4-Nitrophenylamino)-5-aminobenzenesulfonic acidIC5047600.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ 5'-nucleotidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/5-nucleotidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ 5'-nucleotidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/5-nucleotidase-inhibitors-ic50-ki.
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