![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_a26f5906407b17a77b41c8bfb497b4a3.svg) | 3-(3-(Tert-butylthio)-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acid | IC50 | 30.0 [1], 340.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_135f94c345d29248890b053f3f48fb8b.svg) | Quiflapon | IC50 | 200.0 [1], 8000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_d1fa56bccba98bcfb4b5ea939e90fbca.svg) | 3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(pyridin-3-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 1090.0 [1], 17000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_8bca66ffb4cc5c149e4d6d142235c8fa.svg) | 3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-[(6-chloropyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 110.0 [1], 17000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_14f2c2a00c9b7d73967f95ab845fcc8a.svg) | 3-[5-(1,3-Benzothiazol-2-ylmethoxy)-3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 360.0 [1], 10000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_09f335450c54728d768df018632d68d7.svg) | 3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(1,3-thiazol-4-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 40.0 [1], 4000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_5802e70d2a92b8db565d363482e2597e.svg) | 2-[(E)-[3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropylidene]amino]oxyacetic acid | IC50 | 100.0 [1], 680.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_215fbd405907b4e7003e8a69b2ca9eab.svg) | (E)-3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-N-methoxy-2,2-dimethylpropan-1-imine | IC50 | 340.0 [1], 11000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_a9076e7aef0a07baee7bcf984118e37b.svg) | (NE)-N-[3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropylidene]hydroxylamine | IC50 | 270.0 [1], 2200.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_94aff83b6853641fc780b331f921ce4b.svg) | 1-[3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropyl]-1-hydroxyurea | IC50 | 170.0 [1], 1600.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_6a487db64d5c098057caf9a5eed06402.svg) | 3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(naphthalen-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 4420.0 [1], 12000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_9b540976fa7f4a8e2c664fa6431a46a7.svg) | 2-[(E)-[3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-[(6-chloropyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropylidene]amino]oxyacetic acid | IC50 | 230.0 [1], 10000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_18fee6481be99fcb2a1c3dfb0225b34e.svg) | 2-[(E)-[3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(pyridin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropylidene]amino]oxyacetic acid | IC50 | 600.0 [1], 13000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_da86cafa25c49af84573caa65ae11c6b.svg) | 2-[(E)-[3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(1,3-thiazol-4-ylmethoxy)indol-2-yl]-2,2-dimethylpropylidene]amino]oxyacetic acid | IC50 | 180.0 [1], 11000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_a51d425106e6ea52bf17f5a5680b8c84.svg) | [3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropyl]urea | IC50 | 180.0 [1], 970.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_279a030b9d70936ad7709ec22d05e803.svg) | 2-[(E)-[3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropylidene]amino]oxyacetic acid | IC50 | 600.0 [1], 12000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_390d2a24fe034c7121e63cf40ee143dd.svg) | 3-[1-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2-methylpropan-2-yl]-1-hydroxy-1-methylurea | IC50 | 150.0 [1], 1300.0 [2] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_de671703ed16ba064c47e126af4e08ee.svg) | 3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(pyridin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 50.0 [1] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_33226aa7829ab1597eebb6515dabd141.svg) | 3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(pyridin-4-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 840.0 [1] |
![](https://images.aatbio.com/dataset/ic50/5-lipoxygenase-flap_f919fd316972cbd94c34b3e21190000c.svg) | 3-[3-Tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(1,3-thiazol-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid | IC50 | 7000.0 [1] |