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4-hydroxyphenylpyruvate dioxygenase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
NitisinoneKi37.0 [1]
3-(3-Chlorophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi10.0 [1]
3-(2-Bromo-4-methylphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi11.0 [1]
3-(2-Chlorophenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi86.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methyl-3-(2-methylphenyl)quinazolin-4-oneKi248.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(2-methoxyphenyl)-2-methylquinazolin-4-oneKi207.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(2-fluorophenyl)-2-methylquinazolin-4-oneKi79.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methyl-3-(3-methylphenyl)quinazolin-4-oneKi74.0 [1]
3-(3-Chlorophenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi173.0 [1]
3-(3-Bromophenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi93.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(3-fluorophenyl)-2-methylquinazolin-4-oneKi90.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(4-fluorophenyl)-2-methylquinazolin-4-oneKi247.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(4-methoxyphenyl)-2-methylquinazolin-4-oneKi238.0 [1]
3-(4-Bromophenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi130.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methyl-3-(4-methylphenyl)quinazolin-4-oneKi156.0 [1]
3-(4-Chlorophenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi237.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(2,4-dimethylphenyl)-2-methylquinazolin-4-oneKi161.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(2-fluoro-4-methylphenyl)-2-methylquinazolin-4-oneKi81.0 [1]
6-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(4-fluoro-2-methylphenyl)-2-methylquinazolin-4-oneKi219.0 [1]
3-(2-Bromo-4-methylphenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi87.0 [1]
3-(4-Chloro-2-methylphenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi177.0 [1]
3-(2-Chloro-4-methylphenyl)-6-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-2-methylquinazolin-4-oneKi109.0 [1]
2-Methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-phenylquinazolin-4-oneKi19.0 [1]
3-(2-Fluorophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi15.0 [1]
3-(2-Chlorophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi22.0 [1]
3-(2-Bromophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi24.0 [1]
2-Methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(2-methylphenyl)quinazolin-4-oneKi58.0 [1]
3-(2-Methoxyphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi38.0 [1]
3-(3-Fluorophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi20.0 [1]
3-(3-Bromophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi14.0 [1]
2-Methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(3-methylphenyl)quinazolin-4-oneKi13.0 [1]
3-(3-Methoxyphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi34.0 [1]
2-Methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-[3-(trifluoromethoxy)phenyl]quinazolin-4-oneKi31.0 [1]
3-(4-Fluorophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi34.0 [1]
3-(4-Chlorophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi22.0 [1]
3-(4-Bromophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi18.0 [1]
2-Methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(4-methylphenyl)quinazolin-4-oneKi25.0 [1]
3-(4-Methoxyphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi60.0 [1]
2-Methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-[4-(trifluoromethoxy)phenyl]quinazolin-4-oneKi160.0 [1]
3-(4-Chloro-2-methylphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi32.0 [1]
3-(4-Fluoro-2-methylphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi40.0 [1]
3-(3,4-Dichlorophenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi25.0 [1]
3-(2-Fluoro-4-methylphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi170.0 [1]
3-(2-Chloro-4-methylphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi90.0 [1]
3-(2,4-Dimethylphenyl)-2-methyl-6-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)quinazolin-4-oneKi59.0 [1]
3-[2-Nitro-4-(trifluoromethyl)benzoyl]hexane-2,4-dioneIC5068.0 [1]
1-Methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-propylbenzimidazol-2-oneIC5059.0 [1]
3-Butyl-1-methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC50170.0 [1]
1-Methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(2-methylpropyl)benzimidazol-2-oneIC50140.0 [1]
3-Cyclopentyl-1-methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC50130.0 [1]
1-Methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-propan-2-ylbenzimidazol-2-oneIC5061.0 [1]
3-Ethyl-1-methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC5022.0 [1]
3-Tert-butyl-1-methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC50100.0 [1]
1-Methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-(4-methylphenyl)benzimidazol-2-oneIC50250.0 [1]
3-Benzyl-1-methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC50130.0 [1]
3-Cyclopropyl-1-methyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC50100.0 [1]
1-Ethyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-propylbenzimidazol-2-oneIC5022.0 [1]
1,3-Diethyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC5021.0 [1]
1-Ethyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-3-propan-2-ylbenzimidazol-2-oneIC5064.0 [1]
3-Tert-butyl-1-ethyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC50150.0 [1]
3-Cyclopropyl-1-ethyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)benzimidazol-2-oneIC50220.0 [1]
3-Ethyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-1-propylbenzimidazol-2-oneIC5039.0 [1]
5-(2-Methyl-3-oxo-1H-pyrazole-4-carbonyl)-1,3-dipropylbenzimidazol-2-oneIC5040.0 [1]
3-Tert-butyl-5-(2-methyl-3-oxo-1H-pyrazole-4-carbonyl)-1-propylbenzimidazol-2-oneIC5077.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methyl-3-propylbenzimidazol-2-oneIC501030.0 [1]
3-Butyl-5-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methylbenzimidazol-2-oneIC50640.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methyl-3-(2-methylpropyl)benzimidazol-2-oneIC502710.0 [1]
3-Cyclopentyl-5-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methylbenzimidazol-2-oneIC50930.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methyl-3-propan-2-ylbenzimidazol-2-oneIC50940.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-ethyl-1-methylbenzimidazol-2-oneIC50970.0 [1]
3-Tert-butyl-5-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methylbenzimidazol-2-oneIC50990.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methyl-3-(4-methylphenyl)benzimidazol-2-oneIC50990.0 [1]
3-Benzyl-5-(2,5-dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-methylbenzimidazol-2-oneIC50670.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-ethyl-3-propylbenzimidazol-2-oneIC50880.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1,3-diethylbenzimidazol-2-oneIC50940.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1-ethyl-3-propan-2-ylbenzimidazol-2-oneIC50970.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-ethyl-1-propylbenzimidazol-2-oneIC50740.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-1,3-dipropylbenzimidazol-2-oneIC50720.0 [1]
5-(2,5-Dimethyl-3-oxo-1H-pyrazole-4-carbonyl)-3-propan-2-yl-1-propylbenzimidazol-2-oneIC501190.0 [1]
Items per page: 1 - 10 of 79
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References

This online tool may be cited as follows

MLA

"Quest Database™ 4-hydroxyphenylpyruvate dioxygenase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/4-hydroxyphenylpyruvate-dioxygenase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ 4-hydroxyphenylpyruvate dioxygenase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/4-hydroxyphenylpyruvate-dioxygenase-inhibitors-ic50-ki.
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