3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	1-[2-(3-Methoxy-4-(111C)methoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine	Ki	1.7 [1], 1.72 [2]
	Testosterone	Ki	100000.0 [1]
	Progesterone	Ki	100000.0 [1]
	Corticosterone	Ki	100000.0 [1]
	Tamoxifen	Ki	5.0 [1]
	Haloperidol	Ki	190.0 [1]
	Amiodarone	Ki	25.0 [1]
	Raloxifene	Ki	1.0 [1]
	Clomiphene	Ki	1.0 [1]
	Trifluoperazine	Ki	8.0 [1]
	Terbinafine	Ki	50000.0 [1]
	Triparanol	Ki	11.0 [1]
	1,3-Di-o-tolylguanidine	Ki	6700.0 [1]
	Buflomedil	Ki	60.0 [1]
	Opipramol	Ki	13.0 [1]
	Nafoxidine	Ki	0.9 [1]
	Trifluperidol	Ki	165.0 [1]
	(22R,25R)-Spirosol-5-en-3beta-ol	Ki	100000.0 [1]
	Naftifine	Ki	1500.0 [1]
	[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-dipropyl-amine	Ki	15.0 [1]
	Cutamesine	Ki	1.72 [1]
	Fenpropimorph	Ki	30.0 [1]
	Jervine	Ki	100000.0 [1]
	Levemopamil	Ki	18.0 [1]
	4-(2-(4-(3-(4-Chlorophenyl)-2-propenyl)-1-piperazinyl)ethyl)benzoic acid	Ki	34000.0 [1]
	Carbizocaine	Ki	51.0 [1]
	(R)-Preclamol	Ki	2200.0 [1]
	Zuclomiphene	Ki	2.0 [1]
	4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol	Ki	5.0 [1]
	1'-Benzyl-1-(2-fluoroethyl)spiro[1H-2-benzofuran-3,4'-piperidine]	Ki	211.0 [1]
	1'-Benzyl-1-(3-fluoropropyl)spiro[1H-2-benzofuran-3,4'-piperidine]	Ki	455.0 [1]
	Ronipamil	Ki	2.0 [1]
	(22S,25S)-Spirosolan-3beta-ol	Ki	583.0 [1]
	5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-ol	Ki	0.6 [1]
	3beta-(2-(Diethylamino)ethoxy)androst-5-en-17-one	Ki	2.0 [1]
	1'-Butylspiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]	Ki	1.0 [1]
	2-[[Amino(benzylamino)methylene]amino]-4-(1H-indol-2-yl)thiazole	Ki	8500.0 [1]
	2-(2-Benzhydrylsulfanylethyl)-1-[2-(1H-imidazol-5-yl)ethyl]guanidine	Ki	39.0 [1]
	(2r,6s)-2,6-Dimethyl-4-tridecylmorpholine	Ki	1.0 [1]
	(1R,13S)-1,13-Dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol	Ki	500.0 [1]
	(1S,2S,7S,10R,11S,14S,15R,16S,20S,23S)-10,14,16,20-Tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-ol	Ki	441.0 [1]
	2-Chloro-N-[2-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]ethyl]aniline	Ki	4.0 [1]
	(+)-Emopamil	Ki	6.0 [1]
	(3S,3'R,3'As,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',7'a,10,11b-pentamethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3,3a,4,5,6,7-hexahydrofuro[3,2-b]pyridine]-3-ol	Ki	654.0 [1]
	2-[4-[(E)-4-[4-[2-(Diethylamino)ethoxy]phenyl]hex-3-en-3-yl]phenoxy]-N,N-diethylethanamine	Ki	54.0 [1]
	1'-Benzyl-1-(4-fluorobutyl)spiro[1H-2-benzofuran-3,4'-piperidine]	Ki	233.0 [1]
	[(E)-3-(3-Chloro-4-cyclohexyl-phenyl)-allyl]-cyclohexyl-ethyl-amine	Ki	3.0 [1]
	(1R,3Ar,4R,5S,7aR)-5-(dimethylamino)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	17000.0 [1]
	(1R,3Ar,4R,5S,7aR)-5-(benzylamino)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	8000.0 [1]
	(1R,3Ar,4R,5S,7aR)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-5-(pent-4-enylamino)-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	15000.0 [1]
	(1R,3Ar,4R,5S,7aR)-5-[benzyl(methyl)amino]-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	7000.0 [1]
	(1R,3Ar,4R,5S,7aR)-5-(dibenzylamino)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	27000.0 [1]
	(1R,3Ar,4R,5S,7aR)-5-[benzyl(pent-4-enyl)amino]-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	17000.0 [1]
	(1R,3Ar,4R,5S,7aR)-5-amino-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	11000.0 [1]
	(1R,3Ar,4R,5S,7aR)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-5-[methyl(pent-4-enyl)amino]-2,3,4,5,6,7-hexahydro-1H-inden-4-ol	IC50	7000.0 [1]
	(7S,8R)-6-Allylamino-7,8-dimethyl-8-propyl-5,6,7,8-tetrahydro-naphthalen-2-ol	Ki	9300.0 [1]
	Benzothiazol-2-yl-methyl-[1-(4-phenoxy-butyl)-pyrrolidin-3-yl]-amine	Ki	450.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 57 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/3-beta-hydroxysteroid-delta-8-delta-7-isomerase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 22). Quest Database™ 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/3-beta-hydroxysteroid-delta-8-delta-7-isomerase-inhibitors-ic50-ki.
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