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3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-[2-(3-Methoxy-4-(111C)methoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazineKi1.7 [1], 1.72 [2]
TestosteroneKi100000.0 [1]
ProgesteroneKi100000.0 [1]
CorticosteroneKi100000.0 [1]
TamoxifenKi5.0 [1]
HaloperidolKi190.0 [1]
AmiodaroneKi25.0 [1]
RaloxifeneKi1.0 [1]
ClomipheneKi1.0 [1]
TrifluoperazineKi8.0 [1]
TerbinafineKi50000.0 [1]
TriparanolKi11.0 [1]
1,3-Di-o-tolylguanidineKi6700.0 [1]
BuflomedilKi60.0 [1]
OpipramolKi13.0 [1]
NafoxidineKi0.9 [1]
TrifluperidolKi165.0 [1]
(22R,25R)-Spirosol-5-en-3beta-olKi100000.0 [1]
NaftifineKi1500.0 [1]
[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-dipropyl-amineKi15.0 [1]
CutamesineKi1.72 [1]
FenpropimorphKi30.0 [1]
JervineKi100000.0 [1]
LevemopamilKi18.0 [1]
4-(2-(4-(3-(4-Chlorophenyl)-2-propenyl)-1-piperazinyl)ethyl)benzoic acidKi34000.0 [1]
CarbizocaineKi51.0 [1]
(R)-PreclamolKi2200.0 [1]
ZuclomipheneKi2.0 [1]
4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenolKi5.0 [1]
1'-Benzyl-1-(2-fluoroethyl)spiro[1H-2-benzofuran-3,4'-piperidine]Ki211.0 [1]
1'-Benzyl-1-(3-fluoropropyl)spiro[1H-2-benzofuran-3,4'-piperidine]Ki455.0 [1]
RonipamilKi2.0 [1]
(22S,25S)-Spirosolan-3beta-olKi583.0 [1]
5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-olKi0.6 [1]
3beta-(2-(Diethylamino)ethoxy)androst-5-en-17-oneKi2.0 [1]
1'-Butylspiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]Ki1.0 [1]
2-[[Amino(benzylamino)methylene]amino]-4-(1H-indol-2-yl)thiazoleKi8500.0 [1]
2-(2-Benzhydrylsulfanylethyl)-1-[2-(1H-imidazol-5-yl)ethyl]guanidineKi39.0 [1]
(2r,6s)-2,6-Dimethyl-4-tridecylmorpholineKi1.0 [1]
(1R,13S)-1,13-Dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-olKi500.0 [1]
(1S,2S,7S,10R,11S,14S,15R,16S,20S,23S)-10,14,16,20-Tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-olKi441.0 [1]
2-Chloro-N-[2-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]ethyl]anilineKi4.0 [1]
(+)-EmopamilKi6.0 [1]
(3S,3'R,3'As,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',7'a,10,11b-pentamethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3,3a,4,5,6,7-hexahydrofuro[3,2-b]pyridine]-3-olKi654.0 [1]
2-[4-[(E)-4-[4-[2-(Diethylamino)ethoxy]phenyl]hex-3-en-3-yl]phenoxy]-N,N-diethylethanamineKi54.0 [1]
1'-Benzyl-1-(4-fluorobutyl)spiro[1H-2-benzofuran-3,4'-piperidine]Ki233.0 [1]
[(E)-3-(3-Chloro-4-cyclohexyl-phenyl)-allyl]-cyclohexyl-ethyl-amineKi3.0 [1]
(1R,3Ar,4R,5S,7aR)-5-(dimethylamino)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC5017000.0 [1]
(1R,3Ar,4R,5S,7aR)-5-(benzylamino)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC508000.0 [1]
(1R,3Ar,4R,5S,7aR)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-5-(pent-4-enylamino)-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC5015000.0 [1]
(1R,3Ar,4R,5S,7aR)-5-[benzyl(methyl)amino]-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC507000.0 [1]
(1R,3Ar,4R,5S,7aR)-5-(dibenzylamino)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC5027000.0 [1]
(1R,3Ar,4R,5S,7aR)-5-[benzyl(pent-4-enyl)amino]-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC5017000.0 [1]
(1R,3Ar,4R,5S,7aR)-5-amino-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC5011000.0 [1]
(1R,3Ar,4R,5S,7aR)-3a,7a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-5-[methyl(pent-4-enyl)amino]-2,3,4,5,6,7-hexahydro-1H-inden-4-olIC507000.0 [1]
(7S,8R)-6-Allylamino-7,8-dimethyl-8-propyl-5,6,7,8-tetrahydro-naphthalen-2-olKi9300.0 [1]
Benzothiazol-2-yl-methyl-[1-(4-phenoxy-butyl)-pyrrolidin-3-yl]-amineKi450.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/3-beta-hydroxysteroid-delta-8-delta-7-isomerase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/3-beta-hydroxysteroid-delta-8-delta-7-isomerase-inhibitors-ic50-ki.
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