26S proteasome non-ATPase regulatory subunit 14 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Capzimin	IC50	390.0 [1], 600.0 [2], 77400.0 [3]
	N-(1,3-Oxazol-2-yl)-8-[[3-(1,3-oxazol-2-ylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	2600.0 [1], 10000.0 [2]
	N-(2-Morpholin-4-ylethyl)-8-[[3-(2-morpholin-4-ylethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	6400.0 [1], 10000.0 [2]
	N-(1,3-Benzodioxol-5-ylmethyl)-8-[[3-(1,3-benzodioxol-5-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	900.0 [1], 10000.0 [2]
	N-(Pyridin-3-ylmethyl)-8-[[3-(pyridin-3-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	3200.0 [1], 10000.0 [2]
	N-[[4-(Trifluoromethyl)phenyl]methyl]-8-[[3-[[4-(trifluoromethyl)phenyl]methylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	800.0 [1], 10000.0 [2]
	N-(Pyridin-2-ylmethyl)-8-[[3-(pyridin-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	4000.0 [1], 10000.0 [2]
	N-(1,3-Thiazol-2-ylmethyl)-8-[[3-(1,3-thiazol-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	500.0 [1], 2900.0 [2]
	N-[2-(Furan-2-yl)ethyl]-8-[[3-[2-(furan-2-yl)ethylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	1200.0 [1], 1400.0 [2]
	8-[(3-Carbamoylquinolin-8-yl)disulfanyl]quinoline-3-carboxamide	IC50	1000.0 [1], 1200.0 [2]
	N-(Furan-2-ylmethyl)-8-[[3-(furan-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	900.0 [1], 1000.0 [2]
	N-(2-Thiophen-2-ylethyl)-8-[[3-(2-thiophen-2-ylethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	300.0 [1], 5000.0 [2]
	N-(Pyridin-4-ylmethyl)-8-[[3-(pyridin-4-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	200.0 [1], 10000.0 [2]
	N-[(4-Methoxyphenyl)methyl]-8-[[3-[(4-methoxyphenyl)methylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	200.0 [1], 10000.0 [2]
	N-(1,3-Thiazol-2-yl)-8-[[3-(1,3-thiazol-2-ylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	400.0 [1], 1200.0 [2]
	N-(Oxolan-2-ylmethyl)-8-[[3-(oxolan-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	1000.0 [1], 4600.0 [2]
	N-Methyl-8-[[3-(methylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	1600.0 [1], 2600.0 [2]
	N-(Thiophen-2-ylmethyl)-8-[[3-(thiophen-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	800.0 [1], 5000.0 [2]
	N-[(4-Fluorophenyl)methyl]-8-[[3-[(4-fluorophenyl)methylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	200.0 [1], 10000.0 [2]
	8-Methylsulfanyl-N-[2-(1,3-thiazol-2-yl)ethyl]quinoline-3-carboxamide	IC50	40000.0 [1], 100000.0 [2]
	8-[[3-[(4-Morpholin-4-ylphenyl)methylcarbamoyl]quinolin-8-yl]disulfanyl]-N-[(4-piperidin-1-ylphenyl)methyl]quinoline-3-carboxamide	IC50	800.0 [1], 10000.0 [2]
	Methyl 2-[[8-[[3-[(2-methoxy-2-oxoethyl)carbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carbonyl]amino]acetate	IC50	300.0 [1], 2000.0 [2]
	8-Hydroxy-N-[2-(1,3-thiazol-2-yl)ethyl]quinoline-3-carboxamide	IC50	40000.0 [1], 100000.0 [2]
	N-[2-(1,3-Thiazol-2-yl)ethyl]-8-[[7-[2-(1,3-thiazol-2-yl)ethylcarbamoyl]-1,5-naphthyridin-4-yl]disulfanyl]-1,5-naphthyridine-3-carboxamide	IC50	82000.0 [1], 100000.0 [2]
	N-[2-(1,3-Thiazol-2-yl)ethyl]-5-[[2-[2-(1,3-thiazol-2-yl)ethylcarbamoyl]quinolin-5-yl]disulfanyl]quinoline-2-carboxamide	IC50	100000.0 [1]
	Benzyl 2-[[2-[[8-[[3-[[2-oxo-2-[(2-oxo-2-phenylmethoxyethyl)amino]ethyl]carbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carbonyl]amino]acetyl]amino]acetate	IC50	5000.0 [1], 10000.0 [2]
	N-Benzyl-8-[[3-(benzylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	IC50	1100.0 [1], 10000.0 [2]
	8-Hydroxyquinoline	IC50	100000.0 [1]
	8-Aminoquinoline	IC50	100000.0 [1]
	8-Methylquinoline	IC50	100000.0 [1]
	8-Mercaptoquinoline	IC50	2500.0 [1]
	1-Naphthalenethiol	IC50	100000.0 [1]
	8-Quinolinethiol, 2-methyl-	IC50	100000.0 [1]
	4-Methylquinoline-8-thiol	IC50	5700.0 [1]
	5-Methylquinoline-8-thiol	IC50	2500.0 [1]
	8-[(2-Carboxyquinolin-8-yl)disulfanyl]quinoline-2-carboxylic acid	IC50	20000.0 [1]
	N-Benzyl-8-[[2-(benzylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-2-carboxamide	IC50	100000.0 [1]
	N-(Thiophen-2-ylmethyl)-8-[[4-(thiophen-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-4-carboxamide	IC50	1000.0 [1]
	N-(Thiophen-2-ylmethyl)-8-[[2-(thiophen-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-2-carboxamide	IC50	100000.0 [1]
	1,5-Naphthyridine-4-thiol	IC50	15000.0 [1]
	8-Quinolinethiol, 6-methyl-	IC50	900.0 [1]
	5-Quinolinethiol	IC50	100000.0 [1]
	Methyl 8-[(2-methoxycarbonylquinolin-8-yl)disulfanyl]quinoline-2-carboxylate	IC50	50000.0 [1]
	Methyl 8-[(4-methoxycarbonylquinolin-8-yl)disulfanyl]quinoline-4-carboxylate	IC50	1000.0 [1]
	8-Quinolinethiol, 3-methyl-	IC50	1600.0 [1]
	8-(Methylthio)quinoline	IC50	100000.0 [1]
	8-[(3-Carboxy-8-quinolyl)disulfanyl]quinoline-3-carboxylic acid	IC50	1100.0 [1]
	Methyl 8-[(3-methoxycarbonylquinolin-8-yl)disulfanyl]quinoline-3-carboxylate	IC50	900.0 [1]
	8-[(4-Carboxyquinolin-8-yl)disulfanyl]quinoline-4-carboxylic acid	IC50	1300.0 [1]
	N-(Furan-2-ylmethyl)-8-[[4-(furan-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-4-carboxamide	IC50	2200.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 50 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ 26S proteasome non-ATPase regulatory subunit 14 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/26s-proteasome-non-atpase-regulatory-subunit-14-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ 26S proteasome non-ATPase regulatory subunit 14 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/26s-proteasome-non-atpase-regulatory-subunit-14-inhibitors-ic50-ki.
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