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26S proteasome non-ATPase regulatory subunit 14 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
CapziminIC50390.0 [1], 600.0 [2], 77400.0 [3]
N-(1,3-Oxazol-2-yl)-8-[[3-(1,3-oxazol-2-ylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC502600.0 [1], 10000.0 [2]
N-(2-Morpholin-4-ylethyl)-8-[[3-(2-morpholin-4-ylethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC506400.0 [1], 10000.0 [2]
N-(1,3-Benzodioxol-5-ylmethyl)-8-[[3-(1,3-benzodioxol-5-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50900.0 [1], 10000.0 [2]
N-(Pyridin-3-ylmethyl)-8-[[3-(pyridin-3-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC503200.0 [1], 10000.0 [2]
N-[[4-(Trifluoromethyl)phenyl]methyl]-8-[[3-[[4-(trifluoromethyl)phenyl]methylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50800.0 [1], 10000.0 [2]
N-(Pyridin-2-ylmethyl)-8-[[3-(pyridin-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC504000.0 [1], 10000.0 [2]
N-(1,3-Thiazol-2-ylmethyl)-8-[[3-(1,3-thiazol-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50500.0 [1], 2900.0 [2]
N-[2-(Furan-2-yl)ethyl]-8-[[3-[2-(furan-2-yl)ethylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC501200.0 [1], 1400.0 [2]
8-[(3-Carbamoylquinolin-8-yl)disulfanyl]quinoline-3-carboxamideIC501000.0 [1], 1200.0 [2]
N-(Furan-2-ylmethyl)-8-[[3-(furan-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50900.0 [1], 1000.0 [2]
N-(2-Thiophen-2-ylethyl)-8-[[3-(2-thiophen-2-ylethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50300.0 [1], 5000.0 [2]
N-(Pyridin-4-ylmethyl)-8-[[3-(pyridin-4-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50200.0 [1], 10000.0 [2]
N-[(4-Methoxyphenyl)methyl]-8-[[3-[(4-methoxyphenyl)methylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50200.0 [1], 10000.0 [2]
N-(1,3-Thiazol-2-yl)-8-[[3-(1,3-thiazol-2-ylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50400.0 [1], 1200.0 [2]
N-(Oxolan-2-ylmethyl)-8-[[3-(oxolan-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC501000.0 [1], 4600.0 [2]
N-Methyl-8-[[3-(methylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC501600.0 [1], 2600.0 [2]
N-(Thiophen-2-ylmethyl)-8-[[3-(thiophen-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50800.0 [1], 5000.0 [2]
N-[(4-Fluorophenyl)methyl]-8-[[3-[(4-fluorophenyl)methylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC50200.0 [1], 10000.0 [2]
8-Methylsulfanyl-N-[2-(1,3-thiazol-2-yl)ethyl]quinoline-3-carboxamideIC5040000.0 [1], 100000.0 [2]
8-[[3-[(4-Morpholin-4-ylphenyl)methylcarbamoyl]quinolin-8-yl]disulfanyl]-N-[(4-piperidin-1-ylphenyl)methyl]quinoline-3-carboxamideIC50800.0 [1], 10000.0 [2]
Methyl 2-[[8-[[3-[(2-methoxy-2-oxoethyl)carbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carbonyl]amino]acetateIC50300.0 [1], 2000.0 [2]
8-Hydroxy-N-[2-(1,3-thiazol-2-yl)ethyl]quinoline-3-carboxamideIC5040000.0 [1], 100000.0 [2]
N-[2-(1,3-Thiazol-2-yl)ethyl]-8-[[7-[2-(1,3-thiazol-2-yl)ethylcarbamoyl]-1,5-naphthyridin-4-yl]disulfanyl]-1,5-naphthyridine-3-carboxamideIC5082000.0 [1], 100000.0 [2]
N-[2-(1,3-Thiazol-2-yl)ethyl]-5-[[2-[2-(1,3-thiazol-2-yl)ethylcarbamoyl]quinolin-5-yl]disulfanyl]quinoline-2-carboxamideIC50100000.0 [1]
Benzyl 2-[[2-[[8-[[3-[[2-oxo-2-[(2-oxo-2-phenylmethoxyethyl)amino]ethyl]carbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carbonyl]amino]acetyl]amino]acetateIC505000.0 [1], 10000.0 [2]
N-Benzyl-8-[[3-(benzylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamideIC501100.0 [1], 10000.0 [2]
8-HydroxyquinolineIC50100000.0 [1]
8-AminoquinolineIC50100000.0 [1]
8-MethylquinolineIC50100000.0 [1]
8-MercaptoquinolineIC502500.0 [1]
1-NaphthalenethiolIC50100000.0 [1]
8-Quinolinethiol, 2-methyl-IC50100000.0 [1]
4-Methylquinoline-8-thiolIC505700.0 [1]
5-Methylquinoline-8-thiolIC502500.0 [1]
8-[(2-Carboxyquinolin-8-yl)disulfanyl]quinoline-2-carboxylic acidIC5020000.0 [1]
N-Benzyl-8-[[2-(benzylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-2-carboxamideIC50100000.0 [1]
N-(Thiophen-2-ylmethyl)-8-[[4-(thiophen-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-4-carboxamideIC501000.0 [1]
N-(Thiophen-2-ylmethyl)-8-[[2-(thiophen-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-2-carboxamideIC50100000.0 [1]
1,5-Naphthyridine-4-thiolIC5015000.0 [1]
8-Quinolinethiol, 6-methyl-IC50900.0 [1]
5-QuinolinethiolIC50100000.0 [1]
Methyl 8-[(2-methoxycarbonylquinolin-8-yl)disulfanyl]quinoline-2-carboxylateIC5050000.0 [1]
Methyl 8-[(4-methoxycarbonylquinolin-8-yl)disulfanyl]quinoline-4-carboxylateIC501000.0 [1]
8-Quinolinethiol, 3-methyl-IC501600.0 [1]
8-(Methylthio)quinolineIC50100000.0 [1]
8-[(3-Carboxy-8-quinolyl)disulfanyl]quinoline-3-carboxylic acidIC501100.0 [1]
Methyl 8-[(3-methoxycarbonylquinolin-8-yl)disulfanyl]quinoline-3-carboxylateIC50900.0 [1]
8-[(4-Carboxyquinolin-8-yl)disulfanyl]quinoline-4-carboxylic acidIC501300.0 [1]
N-(Furan-2-ylmethyl)-8-[[4-(furan-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-4-carboxamideIC502200.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ 26S proteasome non-ATPase regulatory subunit 14 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.22 Dec2024https://www.aatbio.com/data-sets/26s-proteasome-non-atpase-regulatory-subunit-14-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 22). Quest Database™ 26S proteasome non-ATPase regulatory subunit 14 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/26s-proteasome-non-atpase-regulatory-subunit-14-inhibitors-ic50-ki.
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