2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Adenosine monophosphate	Ki	19200.0 [1]
	Benzyl-adenosine monophosphate	Ki	1900.0 [1]
	[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-phenylphenyl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphate	Ki	500.0 [1]
	3-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]benzoic acid	Ki	2900.0 [1]
	Methyl 3-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]benzoate	Ki	2400.0 [1]
	[(2R,3S,4R,5R)-5-[6-(3-Cyanophenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	4200.0 [1]
	[(2R,3S,4R,5R)-5-[6-(3-Cyanophenoxy)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	93000.0 [1]
	[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-phenylpurin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate	Ki	1500.0 [1]
	[(2R,3S,4R,5R)-5-[6-(4-Cyanophenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	2100.0 [1]
	[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-nitrophenyl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphate	Ki	5300.0 [1]
	4-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]benzoic acid	Ki	2700.0 [1]
	4-[4-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]anilino]-4-oxobutanoic acid	Ki	3700.0 [1]
	[(2R,3S,4R,5R)-5-[6-(Furan-3-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	1700.0 [1]
	[(2R,3S,4R,5R)-5-[6-(5-Formylfuran-2-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	3800.0 [1]
	[(2R,3S,4R,5R)-5-[6-(5-Chlorothiophen-2-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	1300.0 [1]
	[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-quinolin-8-ylpurin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate	Ki	25900.0 [1]
	[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(1H-indol-6-yl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphate	Ki	2500.0 [1]
	[(2R,3S,4R,5R)-5-[6-(5-Bromopyridin-3-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	1600.0 [1]
	[(2R,3S,4R,5R)-5-[6-(3-Bromophenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	1100.0 [1]
	4-[3-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]phenyl]benzoic acid	Ki	1500.0 [1]
	[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-[3-(6-methoxynaphthalen-2-yl)phenyl]purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphate	Ki	500.0 [1]
	[(2R,3S,4R,5R)-5-[6-(3-Dibenzothiophen-4-ylphenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	1400.0 [1]
	[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(4-hydroxyphenyl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphate	Ki	1500.0 [1]
	[(2R,3S,4R,5R)-5-(6-Anilinopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	11200.0 [1]
	6-(Naphthalen-2-Yl)-9-(5-O-Phosphono-beta-D-Ribofuranosyl)-9h-Purine	Ki	2800.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 25 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/2-deoxynucleoside-5-phosphate-n-hydrolase-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/2-deoxynucleoside-5-phosphate-n-hydrolase-1-inhibitors-ic50-ki.
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