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2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Adenosine monophosphateKi19200.0 [1]
Benzyl-adenosine monophosphateKi1900.0 [1]
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-phenylphenyl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphateKi500.0 [1]
3-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]benzoic acidKi2900.0 [1]
Methyl 3-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]benzoateKi2400.0 [1]
[(2R,3S,4R,5R)-5-[6-(3-Cyanophenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi4200.0 [1]
[(2R,3S,4R,5R)-5-[6-(3-Cyanophenoxy)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi93000.0 [1]
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-phenylpurin-9-yl)oxolan-2-yl]methyl dihydrogen phosphateKi1500.0 [1]
[(2R,3S,4R,5R)-5-[6-(4-Cyanophenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi2100.0 [1]
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-nitrophenyl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphateKi5300.0 [1]
4-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]benzoic acidKi2700.0 [1]
4-[4-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]anilino]-4-oxobutanoic acidKi3700.0 [1]
[(2R,3S,4R,5R)-5-[6-(Furan-3-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi1700.0 [1]
[(2R,3S,4R,5R)-5-[6-(5-Formylfuran-2-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi3800.0 [1]
[(2R,3S,4R,5R)-5-[6-(5-Chlorothiophen-2-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi1300.0 [1]
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-quinolin-8-ylpurin-9-yl)oxolan-2-yl]methyl dihydrogen phosphateKi25900.0 [1]
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(1H-indol-6-yl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphateKi2500.0 [1]
[(2R,3S,4R,5R)-5-[6-(5-Bromopyridin-3-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi1600.0 [1]
[(2R,3S,4R,5R)-5-[6-(3-Bromophenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi1100.0 [1]
4-[3-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]phenyl]benzoic acidKi1500.0 [1]
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-[3-(6-methoxynaphthalen-2-yl)phenyl]purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphateKi500.0 [1]
[(2R,3S,4R,5R)-5-[6-(3-Dibenzothiophen-4-ylphenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi1400.0 [1]
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-[6-(4-hydroxyphenyl)purin-9-yl]oxolan-2-yl]methyl dihydrogen phosphateKi1500.0 [1]
[(2R,3S,4R,5R)-5-(6-Anilinopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphateKi11200.0 [1]
6-(Naphthalen-2-Yl)-9-(5-O-Phosphono-beta-D-Ribofuranosyl)-9h-PurineKi2800.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/2-deoxynucleoside-5-phosphate-n-hydrolase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/2-deoxynucleoside-5-phosphate-n-hydrolase-1-inhibitors-ic50-ki.
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