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17-beta-hydroxysteroid dehydrogenase 14 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
(4-Fluoranyl-3-Oxidanyl-Phenyl)-[6-(2-Fluoranyl-3-Oxidanyl-Phenyl)pyridin-2-Yl]methanoneKi13.0 [1]
[6-(3,4-Dihydroxyphenyl)pyridin-2-Yl](4-Fluoro-3-Hydroxyphenyl)methanoneKi7.0 [1]
(4-Fluoranyl-3-Oxidanyl-Phenyl)-[6-(3-Methyl-4-Oxidanyl-Phenyl)pyridin-2-Yl]methanoneKi26.0 [1]
[6-(4-Hydroxy-3-methylphenyl)pyridin-2-yl]-(3-hydroxyphenyl)methanoneKi245.0 [1]
[6-(3-Fluoro-4-hydroxyphenyl)pyridin-2-yl]-(3-hydroxyphenyl)methanoneKi467.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[5-(4-hydroxy-3-methylphenyl)pyridin-2-yl]methanoneKi24.0 [1]
(4-Fluoro-3-hydroxyphenyl)-pyridin-2-ylmethanoneKi1541.0 [1]
[6-[3-(Dimethylamino)phenyl]pyridin-2-yl]-(4-fluoro-3-hydroxyphenyl)methanoneKi7.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[6-(3-hydroxyphenyl)pyridin-2-yl]methanoneKi7.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[5-(3-fluoro-4-hydroxyphenyl)pyridin-2-yl]methanoneKi17.0 [1]
3-[(Z)-[6-(2-Fluoro-3-hydroxyphenyl)-1-hydroxypyridin-2-ylidene]-hydroxymethyl]cyclohexa-3,5-diene-1,2-dioneKi132.0 [1]
(4-Fluoro-3-hydroxyphenyl)-(6-phenoxypyridin-2-yl)methanoneKi50.0 [1]
[6-(2-Fluoro-3-hydroxyphenyl)pyridin-2-yl]-(2-hydroxyphenyl)methanoneKi135.0 [1]
(2,3-Dihydroxyphenyl)-[3-(2-fluoro-3-hydroxyphenyl)phenyl]methanoneKi21.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]methanoneKi190.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[6-(3-hydroxy-4-methylphenyl)pyridin-2-yl]methanoneKi47.0 [1]
(2,4-Difluoro-3-hydroxyphenyl)-[6-(2-fluoro-3-hydroxyphenyl)pyridin-2-yl]methanoneKi9.0 [1]
[6-(3-Chloro-4-fluorophenyl)pyridin-2-yl]-(4-fluoro-3-hydroxyphenyl)methanoneKi190.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[6-(2-fluoro-3-hydroxyphenyl)-4-(hydroxymethyl)pyridin-2-yl]methanoneKi86.0 [1]
(4-Fluoro-3-hydroxyphenyl)-(6-thiophen-3-ylpyridin-2-yl)methanoneKi97.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[6-(4-fluorophenyl)pyridin-2-yl]methanoneKi221.0 [1]
(4-Fluoro-3-hydroxyphenyl)-(6-phenylpyridin-2-yl)methanoneKi63.0 [1]
(4-Fluoro-3-hydroxyphenyl)-(6-piperidin-1-ylpyridin-2-yl)methanoneKi407.0 [1]
2-Fluoro-3-[6-[1-(4-fluoro-3-hydroxyphenyl)ethenyl]pyridin-2-yl]phenolKi1.5 [1]
2-Fluoro-3-[6-(4-fluoro-3-hydroxy-N-methylanilino)pyridin-2-yl]phenolKi42.0 [1]
2-Fluoranyl-3-[6-(4-fluoranyl-3-oxidanyl-phenoxy)pyridin-2-yl]phenolKi58.0 [1]
(4-Fluoranyl-3-oxidanyl-phenyl)-(6-methylquinolin-2-yl)methanoneKi6.0 [1]
(4-Fluoranyl-3-oxidanyl-phenyl)-quinolin-2-yl-methanoneKi12.0 [1]
2-(4-Fluoranyl-3-oxidanyl-phenyl)carbonylquinoline-7-carbonitrileKi9.0 [1]
[2,3-Bis(Oxidanyl)phenyl]-[6-(2-Fluoranyl-3-Oxidanyl-Phenyl)pyridin-2-Yl]methanoneKi64.0 [1]
[4-Fluoranyl-2,3-Bis(Oxidanyl)phenyl]-[6-(2-Fluoranyl-3-Oxidanyl-Phenyl)pyridin-2-Yl]methanoneKi11.0 [1]
[5,6-Bis(4-hydroxy-3-methylphenyl)pyridin-2-yl]-(4-fluoro-3-hydroxyphenyl)methanoneKi9.0 [1]
[6-(2-Fluoro-3-hydroxyphenyl)pyridin-2-yl]-(2,3,6-trihydroxyphenyl)methanoneKi796.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[6-(3-fluoro-4-hydroxyphenyl)pyridin-2-yl]methanoneKi36.0 [1]
[6-(2-Fluoro-3-hydroxyphenyl)pyridin-2-yl]-(2,3,4-trihydroxyphenyl)methanoneKi405.0 [1]
(2,3-Dihydroxyphenyl)-[6-(3-hydroxyphenyl)pyridin-2-yl]methanoneKi44.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[5-(2-fluoro-3-hydroxyphenyl)-6-(4-hydroxy-3-methylphenyl)pyridin-2-yl]methanoneKi15.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[7-(2H-tetrazol-5-yl)quinolin-2-yl]methanoneKi10.0 [1]
2-[[2-(4-Fluoro-3-hydroxybenzoyl)quinolin-7-yl]amino]acetic acidKi23.0 [1]
4-Fluoro-N-[6-(2-fluoro-3-hydroxyphenyl)pyridin-2-yl]-3-hydroxy-N-methylbenzamideKi2030.0 [1]
(4-Fluoro-3-hydroxyphenyl)-naphthalen-2-ylmethanoneKi6.0 [1]
4-Fluoro-N-[6-(2-fluoro-3-hydroxyphenyl)pyridin-2-yl]-3-hydroxybenzamideKi686.0 [1]
6-(2-Fluoro-3-hydroxyphenyl)-N-(4-fluoro-3-hydroxyphenyl)pyridine-2-carboxamideKi336.0 [1]
(4-Fluoro-3-hydroxyphenyl)-[7-(4-hydroxy-3-methylphenyl)quinolin-2-yl]methanoneKi6.0 [1]
(7-Aminoquinolin-2-yl)-(4-fluoro-3-hydroxyphenyl)methanoneKi34.0 [1]
2-Fluoro-3-[6-(4-fluoro-3-hydroxyanilino)pyridin-2-yl]phenolKi47.0 [1]
(4-Fluoro-3-hydroxyphenyl)-(6-hydroxyquinolin-2-yl)methanoneKi119.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ 17-beta-hydroxysteroid dehydrogenase 14 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.22 Dec2024https://www.aatbio.com/data-sets/17-beta-hydroxysteroid-dehydrogenase-14-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 22). Quest Database™ 17-beta-hydroxysteroid dehydrogenase 14 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/17-beta-hydroxysteroid-dehydrogenase-14-inhibitors-ic50-ki.
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