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1-acylglycerol-3-phosphate O-acyltransferase beta Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
6-(5-Chloro-2-ethoxyphenyl)-4-N-(4-chlorophenyl)pyrimidine-2,4-diamineIC5017.0 [1]
6-(5-Chloro-2-methoxyphenyl)-4-N-(4-chlorophenyl)pyrimidine-2,4-diamineIC5054.0 [1]
6-(5-Chloro-2-methoxyphenyl)-2-N-(4-chlorophenyl)pyrimidine-2,4-diamineIC502050.0 [1], 7000.0 [2]
2-(5-Chloro-2-methoxyphenyl)-4-N-(4-chlorophenyl)pyrimidine-4,6-diamineIC507000.0 [1]
4-(1,3-Benzothiazol-2-yl)-2-methylanilineIC5040000.0 [1]
Unii-5TT4A4mblrIC5060.0 [1]
N-[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-propionamideIC501500.0 [1]
2,4-Pyrimidinediamine, 6-(5-chloro-2-methylphenyl)-N4-(4-(trifluoromethyl)phenyl)-IC50140.0 [1]
6-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-[1,3,5]triazine-2,4-diamineIC50260.0 [1]
(4-Chloro-3-(1,5-dimethyl-1H-benzoimidazol-2-yl)-phenyl)-carbamic Acid Methyl EsterIC5011000.0 [1]
N-[4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-2-cyano-acetamideIC5027.0 [1]
[4-Chloro-3-(5-trifluoromethyl-benzooxazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl esterIC50140.0 [1]
(4-Chloro-3-(5-trifluoromethyl-benzothiazol-2-yl)-phenyl)-carbamic Acid Prop-2-ynyl EsterIC5015.0 [1]
[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC501000.0 [1]
(4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl)-carbamic Acid Prop-2-ynyl EsterIC5035.0 [1]
2-Azido-N-[4-chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-acetamideIC50170.0 [1]
6-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-[1,3,5]triazine-2,4-diamineIC5045.0 [1]
(4-Chloro-3-(5-trifluoromethyl-benzothiazol-2-yl)-phenyl)-carbamic Acid Methyl EsterIC50200.0 [1]
[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl esterIC50190.0 [1]
[4-Chloro-3-(5-chloro-1-methyl-1H-benzoimidazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl esterIC5060.0 [1]
Benzenemethanol, 4-((2-amino-6-(5-chloro-2-ethoxyphenyl)-4-pyrimidinyl)amino)-IC5075.0 [1]
6-(5-Chloro-2-ethoxyphenyl)-4-N-(4-nitrophenyl)pyrimidine-2,4-diamineIC5010.0 [1]
4-(5-Chloro-2-methoxy-phenyl)-N-p-tolyl-pyridine-2,6-diamineIC50240.0 [1]
6-(5-Chloro-2-methoxyphenyl)-2-N-(4-chlorophenyl)pyridine-2,4-diamineIC506500.0 [1]
6-(5-Chloro-2-methoxyphenyl)-4-N-(1H-indazol-6-yl)pyrimidine-2,4-diamineIC5080.0 [1]
4-N-(4-Bromophenyl)-6-(5-chloro-2-methylphenyl)pyrimidine-2,4-diamineIC5034.0 [1]
4-[6-Amino-4-(5-chloro-2-ethoxy-phenyl)-pyridin-2-ylamino]-benzaldehydeIC5050.0 [1]
4-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-pyridine-2,6-diamineIC5050.0 [1]
4-(5-Chloro-2-ethoxy-phenyl)-N-p-tolyl-pyridine-2,6-diamineIC50490.0 [1]
4-[6-Amino-4-(5-chloro-2-methoxy-phenyl)-pyridin-2-ylamino]-benzaldehydeIC50260.0 [1]
4-N-(4-Bromophenyl)-6-(5-chloro-2-methoxyphenyl)pyrimidine-2,4-diamineIC5028.0 [1]
6-(5-Chloro-2-methylphenyl)-4-N-(4-chlorophenyl)pyrimidine-2,4-diamineIC5022.0 [1]
6-(5-Chloro-2-methoxyphenyl)-4-N-(4-chlorophenyl)pyridine-2,4-diamineIC5018000.0 [1]
6-(5-Chloro-2-ethoxyphenyl)-4-N-(1H-indazol-6-yl)pyrimidine-2,4-diamineIC5024.0 [1]
{4-[6-Amino-4-(5-chloro-2-ethoxy-phenyl)-pyridin-2-ylamino]-phenyl}-methanolIC5099.0 [1]
N-(4-Bromo-phenyl)-2-(5-chloro-2-methoxy-phenyl)-pyrimidine-4,6-diamineIC508000.0 [1]
6-(5-Bromo-2-methylphenyl)-4-N-(4-bromophenyl)pyrimidine-2,4-diamineIC5018.0 [1]
4-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-pyridine-2,6-diamineIC5040.0 [1]
6-(5-Bromo-2-methylphenyl)-4-N-(4-chlorophenyl)pyrimidine-2,4-diamineIC5031.0 [1]
2-{4-[2-Amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-ethanolIC5028.0 [1]
6-(5-Chloro-2-methoxyphenyl)-4-N-(4-methylphenyl)pyridine-2,4-diamineIC5040000.0 [1]
4-N-(4-Chlorophenyl)-6-(2,5-dichlorophenyl)pyrimidine-2,4-diamineIC5020.0 [1]
2-(5-Chloro-2-methoxy-phenyl)-N-(1H-indazol-6-yl)-pyrimidine-4,6-diamineIC502100.0 [1]
3-{4-[2-Amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-propan-1-olIC50230.0 [1]
6-(5-Chloro-2-methoxyphenyl)-2-N-(4-methylphenyl)pyridine-2,4-diamineIC5029000.0 [1]
6-(5-Chloro-2-methoxyphenyl)-2-N-(1H-indazol-6-yl)pyrimidine-2,4-diamineIC50800.0 [1]
N*4*-(4-Chloro-phenyl)-6-phenyl-pyrimidine-2,4-diamineIC501100.0 [1]
2-[2-Amino-6-(4-chloro-phenylamino)-pyrimidin-4-yl]-4-bromo-phenolIC50450.0 [1]
2-[2-Amino-6-(4-chloro-phenylamino)-pyrimidin-4-yl]-4-chloro-phenolIC5010000.0 [1]
N-[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-butyramideIC502500.0 [1]
N-[4-Chloro-3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]acetamideIC502500.0 [1]
1-{4-[2-Amino-6-(5-bromo-2-ethoxyphenyl)pyrimidin-4-ylamino]phenyl}ethanoneIC5034.0 [1]
(NZ)-N-[1-[4-[[2-amino-6-(5-bromo-2-ethoxyphenyl)pyrimidin-4-yl]amino]phenyl]ethylidene]hydroxylamineIC5084.0 [1]
4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl-boronic acidIC5091.0 [1]
4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-N-hydroxy-benzamideIC5088.0 [1]
4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-benzamideIC50750.0 [1]
But-2-ynyl N-[4-chloro-3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]carbamateIC5075.0 [1]
But-3-ynyl N-[4-chloro-3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]carbamateIC5075.0 [1]
[3-(5-Chloro-benzooxazol-2-yl)-4-methyl-phenyl]-carbamic acid methyl esterIC50550.0 [1]
4-[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenylamino]-butyronitrileIC505000.0 [1]
Methyl N-[4-chloro-3-(5-chloro-1-methylbenzimidazol-2-yl)phenyl]carbamateIC50650.0 [1]
Prop-2-ynyl N-[4-chloro-3-[1-methyl-5-(trifluoromethyl)benzimidazol-2-yl]phenyl]carbamateIC50120.0 [1]
Prop-2-ynyl N-[4-chloro-3-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]phenyl]carbamateIC505200.0 [1]
[4-Chloro-3-(6-methyl-benzothiazol-2-yl)-phenyl]-carbamic acid methyl esterIC5064000.0 [1]
[4-Chloro-3-(4-methyl-benzothiazol-2-yl)-phenyl]-carbamic acid methyl esterIC509000.0 [1]
2-(2-Chloro-5-methoxycarbonylamino-phenyl)-benzooxazole-5-carboxylic acidIC5020000.0 [1]
N-(3-Benzothiazol-2-yl-4-methyl-phenyl)-2-cyano-acetamideIC5070.0 [1]
N-[4-Chloro-3-(5-trifluoromethyl-benzothiazol-2-yl)-phenyl]-2-cyano-acetamideIC5050.0 [1]
1-[4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-3-methyl-ureaIC50950.0 [1]
1-[4-Chloro-3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-3-prop-2-ynylureaIC50100.0 [1]
[4-Chloro-3-(5-hydroxy-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC5020000.0 [1]
N-[4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-2-methylamino-acetamideIC505000.0 [1]
2-Azido-N-[4-chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-acetamideIC50600.0 [1]
N-[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-benzamideIC5040000.0 [1]
N-[4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-2-dimethylamino-acetamideIC505000.0 [1]
Prop-2-ynyl N-[3-(5-chloro-1,3-benzoxazol-2-yl)-4-methylphenyl]carbamateIC50100.0 [1]
Prop-2-ynyl N-[4-chloro-3-(5-hydroxy-1,3-benzoxazol-2-yl)phenyl]carbamateIC502000.0 [1]
[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid isopropyl esterIC5016000.0 [1]
[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid propyl esterIC5012000.0 [1]
[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid allyl esterIC501400.0 [1]
N-[4-Chloro-3-(5-chloro-1-methylbenzimidazol-2-yl)phenyl]-2-cyanoacetamideIC50300.0 [1]
[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid ethyl esterIC501500.0 [1]
[3-(5-Chloro-benzothiazol-2-yl)-4-methyl-phenyl]-carbamic acid prop-2-ynyl esterIC5015.0 [1]
Methyl N-[4-chloro-3-(1,6-dimethylbenzimidazol-2-yl)phenyl]carbamateIC5020000.0 [1]
[4-Chloro-3-(4-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC50500.0 [1]
N-[4-Chloro-3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]pent-4-ynamideIC50500.0 [1]
N-[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-formamideIC505000.0 [1]
N-[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-2-cyano-acetamideIC50100.0 [1]
N-[4-Chloro-3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]pent-4-ynamideIC50100.0 [1]
[4-Fluoro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC5064000.0 [1]
[3-(5-Methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC5064000.0 [1]
[4-Methoxy-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC5064000.0 [1]
[4-Chloro-3-(5-phenyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC5064000.0 [1]
[4-Chloro-3-(5-trifluoromethyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC50800.0 [1]
[4-Chloro-3-(6-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl esterIC50400.0 [1]
N-[4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-2-hydroxy-acetamideIC5031000.0 [1]
N-[4-Chloro-3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]but-2-ynamideIC5020000.0 [1]
N-[4-Chloro-3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]but-2-ynamideIC5020000.0 [1]
2-N-(4-Bromophenyl)-6-(5-chloro-2-methoxyphenyl)pyrimidine-2,4-diamineIC502300.0 [1]
4-N-(4-Chlorophenyl)-6-(5-fluoro-2-methylphenyl)pyrimidine-2,4-diamineIC50150.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ 1-acylglycerol-3-phosphate O-acyltransferase beta Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/1-acylglycerol-3-phosphate-o-acyltransferase-beta-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ 1-acylglycerol-3-phosphate O-acyltransferase beta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/1-acylglycerol-3-phosphate-o-acyltransferase-beta-inhibitors-ic50-ki.
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