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WSP-1 *CAS 1352750-34-5*

Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of WSP-1 *CAS 1352750-34-5* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM178.047 µL890.234 µL1.78 mL8.902 mL17.805 mL
5 mM35.609 µL178.047 µL356.094 µL1.78 mL3.561 mL
10 mM17.805 µL89.023 µL178.047 µL890.234 µL1.78 mL

Molarity calculator

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Citations

View all 2 citations: Citation Explorer
Near-infrared-II photocharging nanozyme for enhanced tumor immunotherapy
Authors: Li, Anshuo and Chu, Shuzhen and Yuan, Meng and Zhang, Jinhui and Liu, Hengrui and Zhu, Yuhui and Xu, Jingyi and Jiang, Xinquan and Xue, Weili
Journal: Journal of Colloid and Interface Science (2024)
Biodegradable calcium sulfide-based nanomodulators for H2S-boosted Ca2+-involved synergistic cascade cancer therapy
Authors: Lin, Chuchu and Huang, Chenyi and Shi, Zhaoqing and Ou, Meitong and Sun, Shengjie and Yu, Mian and Chen, Ting and Yi, Yunfei and Ji, Xiaoyuan and Lv, Feng and others,
Journal: Acta Pharmaceutica Sinica B (2022)

References

View all 2 references: Citation Explorer
Selenium inhibits root elongation by repressing the generation of endogenous hydrogen sulfide in Brassica rapa
Authors: Chen Y, Mo HZ, Zheng MY, Xian M, Qi ZQ, Li YQ, Hu LB, Chen J, Yang LF.
Journal: PLoS One (2014): e110904
In site bioimaging of hydrogen sulfide uncovers its pivotal role in regulating nitric oxide-induced lateral root formation
Authors: Li YJ, Chen J, Xian M, Zhou LG, Han FX, Gan LJ, Shi ZQ.
Journal: PLoS One (2014): e90340
Page updated on November 21, 2024

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Physical properties

Molecular weight

561.65

Solvent

DMSO

Storage, safety and handling

Certificate of OriginDownload PDF
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12352200

CAS

1352750-34-5
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