Protonex™ Blue 450 Acid
Protonex™ Blue 450 dye demonstrated pH-dependent fluorescence. Unlike most of the existing fluorescent dyes that are more fluorescent at higher pH, acidic conditions enhance the fluorescence of Protonex™ Blue 450 dye. The fluorescence of Protonex™ Blue 450 dye increases as pH decreases from neutral to the acidic. The weak fluorescence outside the cell may potentially eliminate the wash steps. Protonex™ Blue 450 dye provides a powerful tool to monitor acidic cell compartments such as endosomes and lysosomes. Protonex™ Blue 450 dye is weakly fluorescent outside the cells, but its fluorescence is significantly enhanced in acidic compartments (such as phagosomes, lysosomes and endosomes). This Protonex™ Blue 450 enables the specific detection of cellular acidic compartments with reduced signal variability and improved accuracy for imaging or flow applications. It can be also used for multiplexing cellular functional analysis with green dyes such as GFP, Fluo-8, calcein, or FITC-labeled antibodies.
References
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Authors: Zhao, Hongwei and Guo, Jingrong and Huai, Jiameng and Li, Ruyue and Han, Hui and Huang, Xiao and Jiang, Yuna and Shuang, Shaomin
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (2024): 124162
Authors: Zhao, Hongwei and Guo, Jingrong and Huai, Jiameng and Li, Ruyue and Han, Hui and Huang, Xiao and Jiang, Yuna and Shuang, Shaomin
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (2024): 124162
Tetraphenylethylene-based AIE nanoprobes for labeling lysosome by two-photon imaging in living cells.
Authors: Zhang, Tiantian and Huang, Yan and Chen, Xiuqin and Zheng, Fangmei and Shen, Yating and Chen, Guizhi and Ye, Qiuhao and Chen, Kuizhi and Xiao, Xiufeng and Peng, Yiru
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (2024): 123630
Authors: Zhang, Tiantian and Huang, Yan and Chen, Xiuqin and Zheng, Fangmei and Shen, Yating and Chen, Guizhi and Ye, Qiuhao and Chen, Kuizhi and Xiao, Xiufeng and Peng, Yiru
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (2024): 123630
A single fluorescent probe to examine the dynamics of mitochondria-lysosome interplay and extracellular vesicle role in ferroptosis.
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Journal: Developmental cell (2024): 517-528.e3
Authors: Wang, Ling-Li and Mai, Yu-Zhuo and Zheng, Ming-Hua and Yan, Guang-Hai and Jin, Jing-Yi
Journal: Developmental cell (2024): 517-528.e3
A lysosome-targeted fluorescent probe for fluorescence imaging of hypochlorous acid in living cells and in vivo.
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Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (2024): 124316
Authors: An, Ke and Fan, Jiaxin and Lin, Bin and Han, Yifeng
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (2024): 124316
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Journal: Talanta (2024): 125581
Authors: Wang, Xiao and Wang, Xuechuan and Bai, Zhongxue and Du, Kaiqiang and Zhang, Junli and Han, Qingxin
Journal: Talanta (2024): 125581
Page created on July 22, 2024, last updated on August 26, 2024