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Cy7.5 tetrazine
Cy7.5 tetrazine is a conjugate formed by attaching a tetrazine molecule to the Cy7.5 fluorophore. This conjugate is particularly valuable in bioorthogonal labeling strategies, where it can react selectively and rapidly with a complementary molecule containing TCO, a strained alkene (typically trans-cyclooctene) in a reaction known as the inverse electron-demand Diels-Alder (IEDDA) reaction. The IEDDA reaction between Cy7.5 tetrazine and a strained alkene group allows for specific and efficient labeling of biomolecules without interfering with native biological processes. This labeling method has gained popularity in biochemistry, cell biology, and imaging studies due to its bioorthogonal nature and compatibility with living systems. Cy7.5 tetrazine can provide a valuable infrared fluorescent tool for labeling and tracking specific molecules or structures of interest. Its IR fluorescence properties also make it suitable for deep tissue imaging applications.
Product family
| Name | Excitation (nm) | Emission (nm) | Extinction coefficient (cm -1 M -1) | Quantum yield | Correction Factor (260 nm) | Correction Factor (280 nm) | Correction Factor (482 nm) | Correction Factor (565 nm) | Correction Factor (650 nm) |
| Cy3.5 tetrazine | 579 | 591 | 150000 | 0.15 | 0.08 | 0.178 | - | - | - |
| Cy5.5 tetrazine | 683 | 703 | 250000 | 0.27 | 0.05 | 0.101 | 0.0017 | 0.047 | 0.454 |
References
View all 50 references: Citation Explorer
Acidic pH-Triggered Live-Cell Lysosome Specific Tracking, Ratiometric pH Sensing, and Multicolor Imaging by Visible to NIR Switchable Cy-7 Dyes.
Authors: Mukherjee, Ayan and Saha, Pranab Chandra and Kar, Samiran and Guha, Pampa and Das, Rabi Sankar and Bera, Tapas and Guha, Samit
Journal: Chembiochem : a European journal of chemical biology (2023): e202200641
Authors: Mukherjee, Ayan and Saha, Pranab Chandra and Kar, Samiran and Guha, Pampa and Das, Rabi Sankar and Bera, Tapas and Guha, Samit
Journal: Chembiochem : a European journal of chemical biology (2023): e202200641
Boosting Dye-Sensitized Luminescence by Enhanced Short-Range Triplet Energy Transfer.
Authors: Zhao, Fei and Hu, Jialing and Guan, Daoming and Liu, Jinyang and Zhang, Xuebo and Ling, Huan and Zhang, Yunxiang and Liu, Qian
Journal: Advanced materials (Deerfield Beach, Fla.) (2023): e2304907
Authors: Zhao, Fei and Hu, Jialing and Guan, Daoming and Liu, Jinyang and Zhang, Xuebo and Ling, Huan and Zhang, Yunxiang and Liu, Qian
Journal: Advanced materials (Deerfield Beach, Fla.) (2023): e2304907
Polymer Vesicles with Integrated Photothermal Responsiveness.
Authors: Luo, Yingtong and Wu, Hanglong and Zhou, Xuan and Wang, Jianhong and Er, Süleyman and Li, Yudong and Welzen, Pascal L W and Oerlemans, Roy A J F and Abdelmohsen, Loai K E A and Shao, Jingxin and van Hest, Jan C M
Journal: Journal of the American Chemical Society (2023): 20073-20080
Authors: Luo, Yingtong and Wu, Hanglong and Zhou, Xuan and Wang, Jianhong and Er, Süleyman and Li, Yudong and Welzen, Pascal L W and Oerlemans, Roy A J F and Abdelmohsen, Loai K E A and Shao, Jingxin and van Hest, Jan C M
Journal: Journal of the American Chemical Society (2023): 20073-20080
Comparison of Five Near-Infrared Fluorescent Folate Conjugates in an Ovarian Cancer Model.
Authors: García de Jalón, Elvira and Kleinmanns, Katrin and Fosse, Vibeke and Davidson, Ben and Bjørge, Line and Haug, Bengt Erik and McCormack, Emmet
Journal: Molecular imaging and biology (2023): 144-155
Authors: García de Jalón, Elvira and Kleinmanns, Katrin and Fosse, Vibeke and Davidson, Ben and Bjørge, Line and Haug, Bengt Erik and McCormack, Emmet
Journal: Molecular imaging and biology (2023): 144-155
Computational Design, Synthesis, and Photochemistry of Cy7-PPG, an Efficient NIR-Activated Photolabile Protecting Group for Therapeutic Applications.
Authors: Alachouzos, Georgios and Schulte, Albert M and Mondal, Anirban and Szymanski, Wiktor and Feringa, Ben L
Journal: Angewandte Chemie (International ed. in English) (2022): e202201308
Authors: Alachouzos, Georgios and Schulte, Albert M and Mondal, Anirban and Szymanski, Wiktor and Feringa, Ben L
Journal: Angewandte Chemie (International ed. in English) (2022): e202201308
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