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Fentanyl succinimidyl ester

Fentanyl succinmidyl ester can be conveniently used to make biological conjugates of fentanyl that are used to develop fentanyl assays and tests. It specifically reacts with aliphatic amines such as lysine residue of proteins under slightly basic conditions (pH 7.5-9.5).

References

View all 9 references: Citation Explorer
A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope.
Authors: Wang, Jiaxing and Ellis, Beverly and Zhou, Bin and Eubanks, Lisa M and Blake, Steven and Janda, Kim D
Journal: Chemical communications (Cambridge, England) (2020): 6551-6554
A chemically contiguous hapten approach for a heroin-fentanyl vaccine.
Authors: Natori, Yoshihiro and Hwang, Candy S and Lin, Lucy and Smith, Lauren C and Zhou, Bin and Janda, Kim D
Journal: Beilstein journal of organic chemistry (2019): 1020-1031
[Study of the Metabolism of New Drugs of Abuse].
Authors: Kanamori, Tatsuyuki
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (2019): 699-704
Use of hepatocytes isolated from a liver-humanized mouse for studies on the metabolism of drugs: application to the metabolism of fentanyl and acetylfentanyl.
Authors: Kanamori, Tatsuyuki and Togawa-Iwata, Yuko and Segawa, Hiroki and Yamamuro, Tadashi and Kuwayama, Kenji and Tsujikawa, Kenji and Inoue, Hiroyuki
Journal: Forensic toxicology (2018): 467-475
In Vitro and In Vivo Metabolite Identification Studies for the New Synthetic Opioids Acetylfentanyl, Acrylfentanyl, Furanylfentanyl, and 4-Fluoro-Isobutyrylfentanyl.
Authors: Watanabe, Shimpei and Vikingsson, Svante and Roman, Markus and Green, Henrik and Kronstrand, Robert and Wohlfarth, Ariane
Journal: The AAPS journal (2017): 1102-1122
Page updated on November 20, 2024

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Physical properties

Molecular weight

491.59

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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Alternative formats